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Cell adhesion molecules and sleep
Neuroscience Research, 2017Cell adhesion molecules (CAMs) play essential roles in the central nervous system, where some families are involved in synaptic development and function. These synaptic adhesion molecules (SAMs) are involved in the regulation of synaptic plasticity, and the formation of neuronal networks. Recent findings from studies examining the consequences of sleep
Emma Kate, O'Callaghan +2 more
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Science, 1983
It has been proposed that cell-cell recognition occurs by means of local cell surface modulation of a small number of proteins rather than by expression of large numbers of different cell surface markers. Several different cell adhesion molecules (CAM's) have now been found in a number of vertebrate species in different tissues such as ...
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It has been proposed that cell-cell recognition occurs by means of local cell surface modulation of a small number of proteins rather than by expression of large numbers of different cell surface markers. Several different cell adhesion molecules (CAM's) have now been found in a number of vertebrate species in different tissues such as ...
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Cell adhesion molecules and the glomerulopathies
The American Journal of Medicine, 1999The kidney possesses a unique architecture that allows it to carry out its function of purifying the blood through filtration and tubular reabsorption and secretion. This structure is established and maintained through the interactions of renal cells with the extracellular matrix (ECM) consisting of the glomerular, Bowman’s capsular, tubular and other ...
S, Adler, H R, Brady
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Cell adhesion molecules and the kidney
Pediatric Nephrology, 1994Cell adhesion molecules (CAMs) have been implicated in various biologic processes, including morphogenesis, immune response, and thrombosis. There are four major groups: integrins, cadherins, immunoglobulin superfamily members, and selectins. Certain CAMs are differentially expressed in the developing, normal, and cancerous kidney.
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Cell adhesion molecules in vasculitis
Current Opinion in Rheumatology, 1997Activation of the vascular endothelium by several different stimuli plays a crucial role in the initiation, localization, and propagation of vascular injury. In vitro studies have demonstrated that activation of cultured vascular endothelial cells renders them hyperadhesive for leukocytes.
J W, Tervaert, C G, Kallenberg
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Cell adhesion molecules at the synapse
Frontiers in Bioscience, 2006Synapses are specialized intercellular junctions whose specificity and plasticity provide the structural and functional basis for the formation and maintenance of the complex neural network in the brain. The number, location, and type of synapses formed are well controlled, since synaptic circuits are formed in a highly reproducible way.
Kimberly, Gerrow, Alaa, El-Husseini
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Glycosyltransferases as cell adhesion molecules
Current Opinion in Cell Biology, 1993Specific glycosyltransferases are believed to be present on the cell surface, where they may function as cell adhesion molecules by binding oligosaccharide substrates on adjacent cell surfaces or in the extracellular matrix. The best studied of these is beta 1,4-galactosyltransferase, which mediates sperm binding to the egg coat and selected cell ...
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Cell adhesion molecules and cancer
Current Opinion in Oncology, 1992Cell adhesion molecules are complex protein and carbohydrate molecules of many different types found on the surfaces of all cells. They are important in many aspects of cell biology including development, differentiation, and motility. These processes are frequently disturbed in cancer and recent work has demonstrated that disturbances in cell adhesion
J, Fawcett, A L, Harris
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Synaptic Cell Adhesion Molecules
2012During development of the nervous system following axon pathfinding, synaptic connections are established between neurons. Specific cell adhesion molecules (CAMs) accumulate at pre- and postsynaptic sites and trigger synaptic differentiation through interactions with intra- and extracellular scaffolds. These interactions are important to align pre- and
Olena, Bukalo, Alexander, Dityatev
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