Results 151 to 160 of about 1,877,814 (364)
Molecular Oncology, EarlyView.Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien +7 more
wiley +1 more source
Cancer Management and Research, 2021 Mariusz Łochowski,1 Justyna Chałubińska-Fendler,2 Izabela Zawadzka,3 Barbara Łochowska,4 Marek Rębowski,1 Daniel Brzeziński,1 Józef Kozak1 1Clinic of Thoracic Surgery and Respiratory Rehabilitation, Medical ...
Łochowski M +6 more
doaj
A hybrid cellular automaton model of cartilage regeneration capturing the interactions between cellular dynamics and scaffold porosity [PDF]
arXiv, 2018 To accelerate the development of strategies for cartilage tissue engineering, models are necessary to study the interactions between cellular dynamics and scaffold (SC) porosity. In experiments, cells are seeded in a porous SC where over a month, the SC slowly degrades while cells divide and synthesize extracellular matrix (ECM) constituents. We use an
arxiv
Blood-Cell Counting: A Series of Observations with the Hématimètre of mm. Hayem and Nachet, and the Hæmacytometer of Dr. Gowers [PDF]
, 1879 Frederick P. Henry, CHAS. B. NANCREDE
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Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Molecular Oncology, EarlyView.Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren +4 more
wiley +1 more source
DLA-Count: Dynamic Label Assignment Network for Dense Cell Distribution Counting [PDF]
arXivCell counting remains a fundamental yet challenging task in medical and biological research due to the diverse morphology of cells, their dense distribution, and variations in image quality. We present DLA-Count, a breakthrough approach to cell counting that introduces three key innovations: (1) K-adjacent Hungarian Matching (KHM), which dramatically ...
arxiv
Improving Object Counting with Heatmap Regulation [PDF]
arXiv, 2018 In this paper, we propose a simple and effective way to improve one-look regression models for object counting from images. We use class activation map visualizations to illustrate the drawbacks of learning a pure one-look regression model for a counting task.
arxiv
Effect of indirubin on white blood cell count of the guinea pig [PDF]
, 1951 B. C. de Landsheere
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Molecular Oncology, EarlyView.CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan +6 more
wiley +1 more source