Results 191 to 200 of about 1,018,944 (267)

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Selective Dry-Off Therapy in Conventional Dairy Farms: The Influence of Quarter-Level Selection Criteria on Postpartum Mastitis and Somatic Cell Count. [PDF]

Animals (Basel)
Ducháček J, Legarová V, Codl R, Rysová LK, Gašparík M, Herman SF, Nejeschlebová H.   +6 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Role of prior HPV infection and CD4 T-cell count in modulating cellular immune responses to a three-dose nonavalent HPV vaccine schedule in PWH receiving ART. [PDF]

BMC Med
Tortellini E, Guardiani M, Carraro A, Ansaldo L, Corazza S, De Maria SG, Garattini S, Barresi M, Belvisi V, Zingaropoli MA, Dominelli F, Falvino C, Mengoni F, Tavelli A, Giambi C, Mastroianni CM, Del Borgo C, Marocco R, Lichtner M.   +18 more
europepmc   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Effectiveness of Antibiotic Regimens in Reducing White Blood Cell Count Within Three to Five Days in Febrile Leukocytosis Treated With Ambulatory Therapy. [PDF]

J Clin Med Res
Tumporn W, Lokeskrawee T, Pruksathorn N, Lawanaskol S, Patumanond J, Chanlaor S, Bumrungpagdee W, Lakdee C.   +7 more
europepmc   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

Comparison of Blood Cell Count Results Between MgSO₄ and K2EDTA. Stability and Accuracy of Platelet Counting With MgSO₄. [PDF]

Int J Lab Hematol
Soulard M, Ketatni H, Croix P, Wuilleme S, Cohen P.   +4 more
europepmc   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Mucositis Pain and Its Temporal Relationship to White Cell Count. [PDF]

Paediatr Anaesth
Douglas C, Morse JD, Anderson BJ.
europepmc   +1 more source