Results 191 to 200 of about 1,061,004 (267)

Investigating lactoferrin and somatic cell count dynamics in early postpartum Shami and Baladi goats. [PDF]

Front Vet Sci
Ali ME, Abdelrahman M, Zakaria AM, Farag BF, Mohamed RH, Fayed H, El-Hamid ISA, Ali F, Gheetas RM, Nour SY, Alsyaad KM, Gao M.   +11 more
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

The Role of Immune Dysregulation Markers in Cardiovascular Risk of People Living with HIV: Association Among Intima Media Changes, CD4/CD8 Ratio, and CD4+ Cell Count Nadir. [PDF]

Viruses
Ceccarelli M, Ricci ED, Muccini C, Galli L, Ferrara S, Tartaglia A, Celesia BM, Manzillo E, Guida A, Di Filippo G, Basile R, Castagna A, Maggi P.   +12 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Circulating CD19 B cell count, myocardial injury and clinical outcomes in patients with heart failure. [PDF]

ESC Heart Fail
Kobayashi Y, Otaki Y, Watanabe T, Yamaguchi R, Ono H, Tachibana S, Sato J, Hashimoto N, Wanezaki M, Kutsuzawa D, Arimoto T, Watanabe M.   +11 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Identifying septic arthritis superimposed on crystalline arthropathy: Is synovial cell count the answer? [PDF]

J Clin Orthop Trauma
Morgan AM, Ferati S, Fong C, Egol K.
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Neural Network-Aided Milk Somatic Cell Count Increase Prediction. [PDF]

Vet Sci
Nagy SÁ, Csabai I, Varga T, Póth-Szebenyi B, Gábor G, Solymosi N.   +5 more
europepmc   +1 more source