Results 81 to 90 of about 2,027,135 (358)

Preoperative systemic inflammation predicts postoperative infectious complications in patients undergoing curative resection for colorectal cancer [PDF]

, 2009
The presence of systemic inflammation before surgery, as evidenced by the glasgow prognostic score (mGPS), predicts poor long-term survival in colorectal cancer. The aim was to examine the relationship between the preoperative mGPS and the development of
CS McArdle, CS McArdle, D C McMillan, DC McMillan, DC McMillan, DC McMillan, DC McMillan, DC McMillan, DJ Hole, E F Leitch, EF Leitch, H Ytting, H Ytting, HJ Nielsen, J H Anderson, JE Crozier, JE Crozier, K Canna, L H Moyes, M Ishizuka, NP Rizk, P G Horgan, P Matthiessen, R F McKee, SF Khuri, T Nozoe, T Welsch, TW Du Clos, V Carstairs, WL Law   +29 more
core   +2 more sources

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Optimizing oropharyngeal swabbing techniques: the relationship between force applied and SARS-CoV-2 detection sensitivity

GMS Hygiene and Infection Control
Aim: Nasopharyngeal and oropharyngeal swabs are essential for diagnosing SARS-CoV-2 infections, with nucleic acid testing (NAT) being the most sensitive method.
Melcher, Peter, Pietsch, Corinna, Bergs, Sandra, Youssef, Yasmin, Rahden, Paul, Hepp, Pierre, Henkelmann, Ralf   +6 more
doaj   +1 more source

Effect of preparation procedures on intensity of radioautographic labeling is studied [PDF]

, 1967
Effects of tissue preparation and extractive procedures on the intensity of radioautographic labeling are presented in terms of mean grain count per cell in cells labeled with tritiated precursors of proteins or nucleic acids.
Baserga, R., Kisieleski, W. E.
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Feasibility of Total White Blood Cells Counts by Visible-Near Infrared Spectroscopy [PDF]

, 2021
Teresa Barroso, Lénio Ribeiro, Hugo Gregório, Filipe Neves dos Santos, Rui C. Martins   +4 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Hematological profile of East African Short-Horn Zebu calves: From birth to 51 weeks of age [PDF]

, 2012
This paper is the first attempt to accurately describe the hematological parameters for any African breed of cattle, by capturing the changes in these parameters over the first 12 months of an animal’s life using a population based sample of calves ...
A. Goddard, A. Jennings, B. L. Penzhorn, B. M. de C. Bronsvoort, BD Perry, C. Booth, C. Muller, D Saror, E. J. Poole, G Pasvol, G Uilenberg, G. Pretorius, H. Kiara, HC Brun-Hansen, I Maudlin, I. Conradie van Wyk, J. A. W. Coetzer, JH Lumsden, JM Mwacharo, JM Mwacharo, JW Harvey, JW Magona, M Mohri, M Mohri, M. E. J. Woolhouse, NC Jain, NM Useh, O. Hanotte, OO Oduye, P Bossche Van den, P. G. Toye, P. Mashego, R Ihaka, RL Nagel, S. M. Thumbi, SYP Shiao, TG Knowles, WB Karesh   +37 more
core   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Modulation of osteoblast cell response through laser surface processing of nylon 6,6 [PDF]

, 2011
With an ageing population demand on medical facilities is growing, especially for bio-implants. Therefore, there is a need for cheaper, more efficient implants. This paper details how CO2 and KrF excimer lasers can be employed to modulate osteoblast cell
Lawrence, Jonathan, Waugh, David
core   +1 more source