Results 211 to 220 of about 12,032,873 (351)

Controlling Trophoblast Cell Fusion in the Human Placenta-Transcriptional Regulation of Suppressyn, an Endogenous Inhibitor of Syncytin-1. [PDF]

Biomolecules, 2023
Sugimoto J, Schust DJ, Sugimoto M, Jinno Y, Kudo Y.   +4 more
europepmc   +1 more source

A-NGR fusion protein induces apoptosis in human cancer cells

, 2018
Azadeh Mohammadi-Farsani, Mehryar Habibi Roudkenar, Majid Golkar, Mohammad Ali Shokrgozar, Ali Jahanian‐Najafabadi, Hossein Khanahmad, Samira Valiyari, Saeid Bouzari   +7 more
openalex   +2 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Cell fusion dynamics: mechanisms of multinucleation in osteoclasts and macrophages. [PDF]

Inflamm Regen
Sabe H, Yahara Y, Ishii M.
europepmc   +1 more source

UPR-induced ovarian cancer cell fusion: a mechanism favoring drug resistance? [PDF]

Oncoscience, 2023
Husein M, Petignat P, Cohen M.
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Meiosis-associated expression patterns during starvation-induced cell fusion in the protist Fisculla terrestris. [PDF]

BMC Biol
Gao S, Solbach MD, Bast J, Dumack K.
europepmc   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Cell-cell fusion in cancer: The next cancer hallmark? [PDF]

Int J Biochem Cell Biol
Shultes PV, Weaver DT, Tadele DS, Barker-Clarke RJ, Scott JG.   +4 more
europepmc   +1 more source

Intrinsic signalling factors associated with cancer cell-cell fusion. [PDF]

Cell Commun Signal, 2023
Dittmar T, Hass R.
europepmc   +1 more source