Results 221 to 230 of about 3,494,106 (354)

Research on individualized drug sensitivity detection technology based on bio-3D printing technology for precision treatment of gastrointestinal stromal tumors. [PDF]

Open Life Sci
Tu YY, Huang ZT, Zhang ZY, Liu DL, Qian HL.   +4 more
europepmc   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Hepatocellular carcinoma drug resistance models. [PDF]

Cancer Cell Int
Xie X, Wang Y, Wang Z, Zhang L, Li J, Li Y.   +5 more
europepmc   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Beyond the brain: exploring the impact of animal models of leptomeningeal disease from solid tumors. [PDF]

Acta Neuropathol Commun
Turunen JR, Kumthekar P, Ahmed AU.
europepmc   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Cytometric comparisons between circulating tumor cells from prostate cancer patients and the prostate-tumor-derived LNCaP cell line

Physical Biology, 2012
D. Lazăr, Edward H. Cho, Madelyn S. Luttgen, Thomas J. Metzner, M. Uson, M. Torrey, M. Gross, P. Kuhn   +7 more
semanticscholar   +1 more source

Perfusion-based ex vivo culture of frozen ovarian cancer tissues with preserved tumor microenvironment. [PDF]

NPJ Precis Oncol
De Luise M, Kurelac I, Coluccelli S, De Leo A, Bartoszek EM, Iorio M, Grillini M, Coadă CA, de Biase D, Marchio L, López MN, Rimmer N, Perrone AM, De Iaco P, Porcelli AM, Heinzelmann V, Martin I, Jacob F, Muraro MG, Gasparre G.   +19 more
europepmc   +1 more source

Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?

Molecular Oncology, EarlyView.
 
Chen‐xi Li, Zhong‐cheng Gong
wiley   +1 more source

The genomic landscape of esophageal squamous cell carcinoma cell lines. [PDF]

Cancer Cell Int
Zhang C, Li C, Su JZ, Zhao K, Shao L, Deng J.   +5 more
europepmc   +1 more source