Results 91 to 100 of about 3,387,066 (378)
Frontiers in Microbiology, 2017 The overexpression of RND-type exporters is one of the main causes of multidrug resistance (MDR) in Gram-negative pathogens. In RND transporters, such as Escherichia coli's main efflux pump AcrB, drug efflux occurs in the porter domain, while protons ...
Martijn Zwama +9 more
doaj +1 more source
Membrane repair against H. pylori promotes cancer cell proliferation [PDF]
, 2010 Membrane repair is a universal response against physical and biological insults and enables cell survival. Helicobacter pylori is one of the most common human pathogens and the first formally recognized bacterial carcinogen associated with gastric cancer.
Chiung-Nien Chen +5 more
core +1 more source
An ultra scale-down analysis of the recovery by dead-end centrifugation of human cells for therapy. [PDF]
, 2014 An ultra scale-down method is described to determine the response of cells to recovery by dead-end (batch) centrifugation under commercially defined manufacturing conditions.
Delahaye, M +3 more
core +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Spatial Dynamic Structures and Mobility in Computation [PDF]
arXiv, 2011 Membrane computing is a well-established and successful research field which belongs to the more general area of molecular computing. Membrane computing aims at defining parallel and non-deterministic computing models, called membrane systems or P Systems, which abstract from the functioning and structure of the cell.
arxiv
flippy: User friendly and open source framework for lipid membrane simulations [PDF]
arXiv, 2023 Animal cells are both encapsulated and subdivided by lipid bilayer membranes. Beyond just acting as boundaries, these membranes' shapes influence the function of cells and their compartments. Physically, membranes are two-dimensional fluids with complex elastic behavior, which makes it impossible, for all but a few simple cases, to predict membrane ...
arxiv
Meteoroid capture cell construction [PDF]
, 1976 A thin membrane covering the open side of a meteoroid capture cell causes an impacting meteoroid to disintegrate as it penetrates the membrane.
High, R. W., Zook, H. A.
core +1 more source
Pattern formation at cellular membranes by phosphorylation and dephosphorylation of proteins [PDF]
, 2016 We consider a classical model on activation of proteins, based in two reciprocal enzymatic biochemical reactions. The combination of phosphorylation and dephosphorylation reactions of proteins is a well established mechanism for protein activation in ...
Alonso Muñoz, Sergio
core +2 more sources
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source
Cep57 is a Mis12-interacting kinetochore protein involved in kinetochore targeting of Mad1–Mad2
Nature Communications, 2016 The spindle assembly checkpoint relies on the accumulation of Mad1-Mad2 at kinetochores, but the mechanism of regulation is not known. Here Zhou et al.
Haining Zhou +4 more
doaj +1 more source