Results 101 to 110 of about 3,387,066 (378)
CCDC74A/B are K-fiber crosslinkers required for chromosomal alignment
BMC Biology, 2019 Background Spindle microtubule organization, regulated by microtubule-associated proteins, is critical for cell division. Proper organization of kinetochore fiber (K-fiber), connecting spindle poles and kinetochores, is a prerequisite for precise ...
Haining Zhou +7 more
doaj +1 more source
Molecular Oncology, 2021 Oncogenic KRAS mutations develop unique metabolic dependencies on nutrients to support tumor metabolism and cell proliferation. In particular, KRAS mutant cancer cells exploit amino acids (AAs) such as glutamine and leucine, to accelerate energy ...
Palanivel Kandasamy +7 more
doaj +1 more source
Synthesis of extracellular matrix components by human ciliary muscle cells in culture [PDF]
, 1992 The production and spatial organization of connective tissue components in ciliary muscle cell cultures was studied with immunohistochemical and ultrastructural methods.
Baur, A. +2 more
core +1 more source
Cell Membrane Coated Particles
Advanced Biosystems, 2020 AbstractNanoformulations are widely considered in the biomedical field for drug delivery, imaging, or detoxification purposes. Cell membrane coatings are a growing concept that aims to camouflage nanomaterials. The cell membranes are the first point of contact for cells to other biological or synthetic materials and nature has established signaling ...
Spanjers, Järvi M., Städler, Brigitte
openaire +3 more sources
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Membrane dynamics and cell polarity: the role of sphingolipids
Journal of Lipid Research, 2003 In recent years, glycosphingolipids (GSLs) have attracted widespread attention due to the appreciation that this class of lipids has a major impact on biological life.
Dick Hoekstra +4 more
doaj
Budded membrane microdomains as regulators for cellular tension [PDF]
arXiv, 2005 We propose a mechanism for mechanical regulation at the membrane of living cells, based on the exchange of membrane area between the cell membrane and a membrane reservoir. The reservoir is composed of invaginated membrane microdomains which are liable to flatten upon increase of membrane strain, effectively controlling membrane tension.
arxiv
Dynamics of membranes driven by actin polymerization [PDF]
, 2005 A motile cell, when stimulated, shows a dramatic increase in the activity of its membrane, manifested by the appearance of dynamic membrane structures such as lamellipodia, filopodia and membrane ruffles. The external stimulus turns on membrane bound activators, like Cdc42 and PIP2, which cause increased branching and polymerization of the actin ...
arxiv +1 more source
Cell mechanics and signalisation: SARS-CoV-2 hijacks membrane liquid crystals and cytoskeletal fractal topology [PDF]
arXiv, 2021 We highlight changes to cell signalling under virus invasion (SARS-CoV-2), involving disturbance of membranes and of nanodomains, modulated by the cytoskeleton. Virus alters the mechanical properties of the membranes, impairing mesophase structures mediated by the fractal architecture initiated by actomyosin.
arxiv
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source