Results 141 to 150 of about 15,034,981 (403)

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Syndecan-4 negatively regulates antiviral signalling by mediating RIG-I deubiquitination via CYLD

Nature Communications, 2016
Syndecans are transmembrane proteoglycans implicated in diverse cellular activities. Here the authors show that Syndecan-4 via its cytosolic domain negatively regulates antiviral immunity by enhancing RIG-I interaction with a deubiquitinating enzyme CYLD,
Wei Lin, Jing Zhang, Haiyan Lin, Zexing Li, Xiaofeng Sun, Di Xin, Meng Yang, Liwei Sun, Lin Li, Hongmei Wang, Dahua Chen, Qinmiao Sun   +11 more
doaj   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Mammalian cell membranes [PDF]

Nature, 1977
Mammalian Cell Membranes. Vol. 4: Membranes and Cellular Functions. Pp. 262. Vol. 5: Responses of Plasma Membranes. Pp. 260. Edited by G. A. Jamieson and D. M. Robinson. (Butterworths: London and Boston, Massachusetts, 1977.) £18 each volume.
openaire   +2 more sources

Macrophage Cell Membrane Camouflaged Au Nanoshells for in Vivo Prolonged Circulation Life and Enhanced Cancer Photothermal Therapy.

ACS Applied Materials and Interfaces, 2016
Macrophage cell membrane (MPCM)-camouflaged gold nanoshells (AuNS) that can serve as a new generation of photothermal conversion agents for in vivo photothermal cancer therapy are presented.
Mingjun Xuan, Jingxin Shao, L. Dai, Junbai Li, Q. He   +4 more
semanticscholar   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Spectroscopic investigation of local mechanical impedance of living cells

, 2013
The mechanical properties of PC12 living cells have been studied at the nanoscale with a Force Feedback Microscope using two experimental approaches. Firstly, the local mechanical impedance of the cell membrane has been mapped simultaneously to the cell ...
Benseny-Cases, Núria, Chevrier, Joël, Comin, Fabio, Costa, Luca, Mayeaux, Véronique, Rodrigues, Mario S.   +5 more
core   +5 more sources

Rotating Membrane Cell [PDF]

Science, 1968
T. M. Regan, Charles F. Streckfus, W. G. Esmond, A. M. Wolbarsht   +3 more
openaire   +3 more sources

Cell Membrane Bioconjugation and Membrane-Derived Nanomaterials for Immunotherapy.

Bioconjugate chemistry, 2018
Cell membrane engineering, including live cell membrane bioconjugation and cell membrane-derived nanomaterials is a highly promising strategy to modulate immune responses for treating diseases.
Peter Y. Li, Z. Fan, Hao Cheng
semanticscholar   +1 more source

Maintenance of Semipermeability of Plant Cell Membranes in the Absence of Metabolic Energy Supply [PDF]

, 1959
B. Z. Ginzburg
openalex   +1 more source