Results 181 to 190 of about 3,609,152 (355)

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Engineered hybrid cell membrane nanosystems for treating cardiovascular diseases. [PDF]

Mater Today Bio
Lu H, Jiang Y, Luo R, Zhou D, Zheng F, Shi L, Zhang H, Wang Y, Xu X, Zou R, Zhou Y, Ren S, Wang X, Sang H.   +13 more
europepmc   +1 more source

Is the Cell Membrane a Universal Rate-Limiting Barrier to the Movement of Water between the Living Cell and Its Surrounding Medium? [PDF]

, 1967
Gilbert N. Ling, Margaret M. Ochsenfeld, George Karreman   +2 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

DNA Tweezers with Replaceable Clamps for the Targeted Degradation of Cell Membrane Proteins. [PDF]

Pharmaceutics
Sun Y, Huang Y, Chen D, Hu S, Pan T, Liu Y, Wang R, Tan W.   +7 more
europepmc   +1 more source

Birefringence of Cytoplasm and Cell Membranes

, 1951
M. M. Swann, J. M. Mitchison
openalex   +1 more source

Biosynthesis of glycoproteins of the Ehrlich ascites carcinoma cell membranes. [PDF]

, 1965
Geoffrey M.W. Cook, Marion T. Laico, E.H. Eylar   +2 more
openalex   +1 more source

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source

Advancements in Cell Membrane-Derived Biomimetic Nanotherapeutics for Breast Cancer. [PDF]

Int J Nanomedicine
Zeng M, Hu C, Chen T, Zhao T, Dai X.
europepmc   +1 more source

CARDIAC MEMBRANE POTENTIALS RECORDED FROM THE INJURED VENTRICULAR CELLS OF DOGS

, 1959
Gou Ueda
openalex   +2 more sources