Results 191 to 200 of about 4,055,008 (348)

In vivo Thermodynamics of RTKS in the Cell Membrane: Quantitative Spectral FRET [PDF]

, 2015
Christopher King, Kalina Hristova
openalex   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Biomimetic cell membrane decorated calcium carbonate nanoparticles with asparaginase-metformin preloading for leukemia therapy. [PDF]

J Nanobiotechnology
Gao G, Che J, Chen B, Zhao Y.
europepmc   +1 more source

Some aspects of gaseous hydrogen storage and the performance of a 10-kW Polymer Electrolyte Membrane Fuel Cells stack as part of a hybrid power source

, 2019
Magdalena Dudek, Andrzej Raźniak, Piotr Dudek, M. Korkosz, P. Wygonik, P. Bogusz, Wojciech Frączek   +6 more
openalex   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Development of Dendritic Cell Membrane-Coated Nanoparticles for Antigen-Specific T-Cell Engagement. [PDF]

ACS Biomater Sci Eng
Puth S, Jadhav SS, Zareein A, Blauser-Wilson J, Mahmoudi M, Betanzos RR, Ventura B, Sprague-Getsy AM, Hu X, Hougland JL, Wu Y.   +10 more
europepmc   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Cancer Cell Membrane-Coated NPs as a Biomimetic Strategy for Precision Tumor Therapy. [PDF]

Pharmaceutics
Lin J, Li W, Aboushanab AR, Sun J.
europepmc   +1 more source

Maintaining local alkalinity of CO-electroreduction full cell by silica-confined electrocatalysts in membrane electrode assembly

Shuangxi Jing, Gongwei Wang, Zhe Li, Wei Xiao, Lin Zhuang   +4 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source