EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche+8 more
wiley +1 more source
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner+6 more
wiley +1 more source
The Lamellar Systems of Cytoplasmic Membranes in Dividing Spermatogenic Cells of Drosophila virilis [PDF]
Susumu Ito
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Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon+13 more
wiley +1 more source
DNA Tweezers with Replaceable Clamps for the Targeted Degradation of Cell Membrane Proteins. [PDF]
Sun Y+7 more
europepmc +1 more source
On the Images of Endocrine Function in the Surface-cells of the Gastric Mucous Membrane
Kimio FUJIE, Kaitaro FURUTA, Taizo SATOH
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NORMAL EPIDERMAL BASAL CELL BEHAVIOR IN THE ABSENCE OF BASEMENT MEMBRANE [PDF]
Frances Kallman+2 more
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In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková+14 more
wiley +1 more source
Advancements in Cell Membrane-Derived Biomimetic Nanotherapeutics for Breast Cancer. [PDF]
Zeng M, Hu C, Chen T, Zhao T, Dai X.
europepmc +1 more source
On the Mechanism of Na+- and K+-Stimulated Hydrolysis of Adenosine Triphosphate. 2. Comparison of Nucleotide Specificities of Na+- and K+-Activated ATPase and Na+-Dependent Phosphorylation of Cell Membranes [PDF]
W. Schöner+2 more
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