Results 251 to 260 of about 15,661,277 (406)

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Cell Membrane- and Vesicle-Based Bionic Nanodrugs: Applications in Central Nervous System Diseases and Exploration of Nasal-Cerebral Delivery. [PDF]

Gels
Ding F, Hou R, Han B, Fang X.
europepmc   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Optimization of Cell Membrane Purification for the Preparation and Characterization of Cell Membrane Liposomes. [PDF]

Small Methods
de Weerd S, Ruiter EA, Calicchia E, Portale G, Schuringa JJ, Roos WH, Salvati A.   +6 more
europepmc   +1 more source

Influenza M2 Proton Channel Activity Selectively Inhibits Trans-Golgi Network Release of Apical Membrane and Secreted Proteins in Polarized Madin-Darby Canine Kidney Cells [PDF]

, 2000
Jennifer R. Henkel, Gregory A. Gibson, Paul A. Poland, Mark Ellis, Rebecca P. Hughey, Ora A. Weisz   +5 more
openalex   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Bacterial cell membrane models: choosing the lipid composition.

Soft Matter
Martin AL, Jemmett PN, Howitt T, Wood MH, Cox LR, Dafforn TR, Campana M, Welbourn RJL, Skoda MWA, Clifton LA, Hussain H, Rawle JL, Carlà F, Nicklin CL, Arnold T, Horswell SL.   +15 more
europepmc   +1 more source

Synthesis and antibacterial evaluation of trisindolines against methicillin-resistant Staphylococcus aureus targeting cell membrane. [PDF]

NPJ Biofilms Microbiomes
Rathore A, Zargar IA, Kumari J, Sarkar B, Manhas R, Firdous S, Pandian R, Mukherjee D, Mahapa A.   +8 more
europepmc   +1 more source

CaV1.3 channel clusters characterized by live-cell and isolated plasma membrane nanoscopy [PDF]

Niko Schwenzer, Nikolas K. Teiwes, Tobias Kohl, Celine Pohl, Michelle J. Giller, Stephan E. Lehnart, Claudia Steinem   +6 more
openalex   +1 more source

Toward an Energy Efficient Wastewater Treatment: Combining a Microbial Fuel Cell/Electrolysis Cell Anode With an Anaerobic Membrane Bioreactor [PDF]

, 2018
Nazlı Pelin Kocatürk‐Schumacher, Joana Madjarov, Pavaris Viwatthanasittiphong, Sven Kerzenmacher   +3 more
openalex   +1 more source