The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
A 10 km time trial running bout acutely increases the number of angiogenic T cells in the peripheral blood compartment of healthy males [PDF]
, 2016 Mark Ross +5 more
openalex +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Evolution of secondary cell number and position in the Drosophila accessory gland. [PDF]
PLoS One, 2023 Takashima YA, Majane AC, Begun DJ.
europepmc +1 more source
Control of the number of cell division rounds in distinct tissues during ascidian embryogenesis [PDF]
, 2014 Atsuko Yamada, Hiroki Nishida
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“Copy number alteration” as the sole molecular finding of a Thyroseq test is more commonly seen in Hurthle cell neoplasms [PDF]
, 2023 Teresa Kim +3 more
openalex +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Acute Laryngitis in the Rat Induced by Moraxella catarrhalis and Bordetella pertussis: Number of Neutrophils, Dendritic Cells, and T and B Lymphocytes Accumulating during Infection in the Laryngeal Mucosa Strongly Differs in Adjacent Locations [PDF]
, 1999 Peter Jecker +6 more
openalex +1 more source
Ibrutinib treatment improves T cell number and function in CLL patients
Journal of Clinical Investigation, 2017 M. Long +19 more
semanticscholar +1 more source