Results 221 to 230 of about 14,214,307 (355)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Human Lung Cell Separation Strategies for Translational Research. [PDF]

Am J Respir Cell Mol Biol
Fujino N, Yamada M, Saito T, Konno S, Sugiura H.   +4 more
europepmc   +1 more source

Surgery assistance system for continuous resection of brain tumors-proposal of continuous tumor resection forceps, tumor cell separation, dehydration, and isolation mechanism. [PDF]

Int J Comput Assist Radiol Surg, 2023
Koguchi T, Shimizu F, Nagame T, Goto Y, Iwasaki H, Hanafusa A, Takagi M, Mohamaddan S, Nomura K, Muragaki Y, Iseki H, Masamune K, Akitaya T.   +12 more
europepmc   +1 more source

Fifty years of dielectrophoretic cell separation technology.

Biomicrofluidics, 2016
M. Hughes
semanticscholar   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Advances in Cell Separation: Harnessing DNA Nanomaterials for High-Specificity Recognition and Isolation. [PDF]

Chem Bio Eng
Bao H, Yao Y, Tang W, Yang D.
europepmc   +1 more source

Polygalacturonase activity promotes aberrant cell separation in the quasimodo2 mutant of Arabidopsis thaliana. [PDF]

Cell Surf, 2022
Barnes WJ, Zelinsky E, Anderson CT.
europepmc   +1 more source

High-throughput and clogging-free microfluidic filtration platform for on-chip cell separation from undiluted whole blood.

Biomicrofluidics, 2016
Yinuo Cheng, X. Ye, Zengshuai Ma, Shuai Xie, Wenhui Wang   +4 more
semanticscholar   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

The characteristics of autolysins associated with cell separation in Bacillus subtilis. [PDF]

J Bacteriol
Li R, Chu R, Ban R.
europepmc   +1 more source