Results 151 to 160 of about 3,286,390 (370)

Cancer cell wound contamination associated with surgical therapy of carcinoma of the cervix [PDF]

open access: bronze, 1963
Robert R. Smith   +3 more
openalex   +1 more source

Could Upregulated Hsp70 Protein Compensate for the Hsp90-Silence-Induced Cell Death in Glioma Cells? [PDF]

open access: yes, 2014
The molecular chaperone heat shock protein 90 alpha (Hsp90α) has been recognized in various tumours including glioma. This pilot study using a proteomic approach analyses the downstream effects of Hsp90 inhibition using 17-allylamino-17 ...
Khan, Zarine Jamsher   +3 more
core   +2 more sources

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

open access: yesMolecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen   +13 more
wiley   +1 more source

Conditional Success of Adaptive Therapy: The Role of Treatment-Holiday Thresholds Revealed by Mathematical Modeling [PDF]

open access: yesarXiv
Adaptive therapy (AT) improves cancer treatment by controlling the competition between sensitive and resistant cells through treatment holidays. This study highlights the critical role of treatment-holiday thresholds in AT for tumors composed of drug-sensitive and resistant cells.
arxiv  

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha   +6 more
wiley   +1 more source

Cell Therapy for Epilepsy

open access: yes, 2017
Epilepsy is one of the most common chronic neurological conditions that affects about 1% of the world population. One third of the epilepsies are refractory to medical treatment, and, therefore, it is important to search for alternative treatments. One of these alternative approaches could be cell therapy. In this chapter, we provide an overview of the
M. Simonato, C. Falcicchia, G. Paolone
openaire   +3 more sources

Uncovering How Occupational Therapy Could Benefit Individuals Living with Sickle Cell Disease in Ghana [PDF]

open access: yes, 2018
In 2017, with funding from a Summer Undergraduate Research Fellowship (SURF), I spent ten weeks in Kumasi, Ghana conducting research on how occupational therapy may be beneficial for individuals living with sickle cell disease.
D\u27Olympio, Carolyn
core   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

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