Results 161 to 170 of about 3,286,390 (370)
Intracellular localisation of mTHPC and effect of photodynamic therapy in cells of the mammalian peripheral nervous system [PDF]
, 2007 Fewer nerve-related side effects have been noted after treating head and neck cancer with photodynamic therapy (PDT) compared to conventional cancer therapy. Our aim is to investigate the biological basis for any such nerve-sparing effect.
MacRobert, A. J. +2 more
core
Unraveling the metastasis‐preventing effect of miR‐200c in vitro and in vivo
Molecular Oncology, Volume 19, Issue 4, Page 1029-1053, April 2025.Advanced tumors and ineffective cancer treatments can lead to metastases in distant organs. The sole expression of microRNA 200c (miR‐200c) in breast cancer cells is shown to significantly reduce metastasis formation in xenograft mouse models. Various in vitro analyses revealed impeded migratory behavior, upon miR‐200c expression, as one prerequisite ...
Bianca Köhler +12 more
wiley +1 more source
Granulocyte transfusion therapy of experimental Pseudomonas septicemia: study of cell dose and collection technique [PDF]
, 1978 FR Appelbaum +3 more
openalex +1 more source
Molecular Oncology, EarlyView.This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke +12 more
wiley +1 more source
Low probability Bid-Bax reaction generates heterogeneity in apoptosis resistance of cancer and cancer stem cells [PDF]
arXiv, 2011 Variability in the tumorigenic potential among cancer cells within a tumor population is an unresolved fundamental issue in cancer biology. It is important to know whether cancer cells with higher tumorigenic potential, such as cancer stem cells, are only a small subpopulation.
arxiv
Perturbation of Generation Cycle of Human Leukemic Blast Cells by Cytostatic Therapy In Vivo: Effect of Corticosteroids [PDF]
, 1970 Peter B. Ernst, Sven‐Aage Killmann
openalex +1 more source
Molecular Oncology, Volume 19, Issue 5, Page 1422-1435, May 2025.The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina +17 more
wiley +1 more source
Nonlinear dynamics of CAR-T cell therapy [PDF]
arXivChimeric antigen receptor T-cell (CAR-T) therapy is considered a promising cancer treatment. The dynamic response to this therapy can be broadly divided into a short-term phase, ranging from weeks to months, and a long-term phase, ranging from months to years.
arxiv
Molecular Oncology, Volume 19, Issue 4, Page 1155-1169, April 2025.We propose an efficient strategy to suppress ALK inhibitor (ALKi) resistance. By analyzing transcriptome data, we identified emetine as a potential inhibitor. We demonstrated that emetine exhibited effectiveness in inhibiting the growth of ALKi‐resistant cells, and further interpreted its impact on the resistant signatures through drug‐induced RNA ...
Sang‐Min Park +8 more
wiley +1 more source
Mediterranean Journal of Hematology and Infectious Diseases, 2014 Hematopoietic Stem Cell Transplant is the standard treatment of refractory / recurrent lymphomas, most of conditioning regimens in this cases are BCNU-based as for BEAM & CBV , this agent (BCNU) is well-known for its severe lung toxicity .
Mohamed BEKADJA +7 more
doaj