Results 181 to 190 of about 3,286,390 (370)

Expert Consensus on Adjuvant Therapy of Non-small Cell Lung Cancer from China Thoracic Surgeons (2018 Version)

open access: yesChinese Journal of Lung Cancer, 2018
Thoracic Surgery Committee on Adjuvant Therapy of Non-small Cell Lung Cancer
doaj   +1 more source

A mathematical model of CAR-T cell therapy in combination with chemotherapy for malignant gliomas [PDF]

open access: yesarXiv
We study the dynamics and interactions between combined chemotherapy and chimeric antigen receptor (CAR-T) cells therapy and malignant gliomas (MG). MG is one of the most common primary brain tumor, with high resistance to therapy and unfavorable prognosis.
arxiv  

Red cell aplasia following prolonged D-penicillamine therapy. [PDF]

open access: bronze, 1976
John L. Gollan   +3 more
openalex   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Replenishing co‐downregulated miR‐100‐5p and miR‐125b‐5p in malignant germ cell tumors causes growth inhibition through cell cycle disruption

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 1203-1228, April 2025.
MiR‐99a‐5p/miR‐100‐5p (functionally identical) and miR‐125b‐5p microRNAs are downregulated in malignant germ cell tumors (GCTs). Combination replenishment of these microRNAs using mimics resulted in growth inhibition in representative cell lines, with consequent downregulation of target genes involved in cell cycle (confirmed by flow cytometry) and ...
Marta Ferraresso   +12 more
wiley   +1 more source

Simulating cell populations with explicit cell cycle length -- implications to cell cycle dependent tumour therapy [PDF]

open access: yesarXiv
In this study, we present a stochastic simulation model designed to explicitly incorporate cell cycle length, overcoming limitations associated with classical compartmental models. Our approach employs a delay mechanism to represent the cell cycle, allowing the use of arbitrary distributions for cell cycle lengths. We demonstrate the feasibility of our
arxiv  

Cell Cycle Kinetics and Radiation Therapy [PDF]

open access: green, 1975
Mortimer L. Mendelsohn
openalex   +1 more source

Gut microbiota diversity is prognostic and associated with benefit from chemo‐immunotherapy in metastatic triple‐negative breast cancer

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 1229-1243, April 2025.
We assessed the associations between the gut microbiota and outcome in metastatic triple‐negative breast cancer patients treated with chemotherapy alone or chemotherapy in combination with immunotherapy. Our data indicate that high gut microbiota alpha diversity was associated with improved clinical outcome and with benefit from immunotherapy.
Andreas Ullern   +8 more
wiley   +1 more source

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