Results 311 to 320 of about 3,286,390 (370)

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

CDC25A inhibition sensitizes melanoma cells to doxorubicin and NK cell therapy. [PDF]

Cell Death Dis
Gao X, Liu F, Zhang B, Ren T, Zheng Y, Niu Z, Ren H, Liu C, Jiang C, Wang C, Huang H, Ma L, Sun Q.   +12 more
europepmc   +1 more source

VP-16 SALVAGE THERAPY FOR PVB REGIMEN-RESISTANT TESTICULAR GERM CELL TUMORS

, 1987
Haruki Yamazaki, Y Akasaka, Naoya Kondo, Keiichiro Imanaka, Toyohei Machida   +4 more
openalex   +2 more sources

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Anti-CD19 CAR-T cell therapy for acquired hemophilia A. [PDF]

Leukemia
Schultze-Florey CR, Thol FR, Aleksandrova K, Stoyanov K, Gutierrez Jauregui R, Arseniev L, Leise J, Klöß S, Heidel FH, Tiede A.   +9 more
europepmc   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

EEG as a predictive biomarker of neurotoxicity in anti-CD19 CAR T-cell therapy. [PDF]

J Neurol
Pondrelli F, Muccioli L, Mason F, Zenesini C, Ferri L, Asioli GM, Rossi S, Rinaldi R, Rondelli F, Nicodemo M, D'Angelo R, Barone V, Sambati L, Pensato U, Zinzani PL, Casadei B, Bonifazi F, Maffini E, Pierucci E, Cortelli P, Tinuper P, Bisulli F, Guarino M.   +22 more
europepmc   +1 more source

Application of upper alf body irradiation (UHBI) and cyclophosphamide (CP) as adjuvant therapy in non-small cell bronchogenic carcinoma (NSCBC)

, 1984
Charles W. Scarantino, Frederick Richards, Milton Raben, Carolyn Ferree, Christina Kovacs, W Olds   +5 more
openalex   +1 more source

Enhancing patient engagement in cancer research: a focus on patient‐centric approaches to scientific discovery

Molecular Oncology, EarlyView.
Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda, Marina Reguero, Vanesa Abón, Marta Puyol   +3 more
wiley   +1 more source

Cell therapy in Sjögren's syndrome: opportunities and challenges. [PDF]

Expert Rev Mol Med
Lu Y, Shi R, He W, An Q, Zhao J, Gao X, Zhang B, Zhang L, Xu K, Ma D.   +9 more
europepmc   +1 more source