Results 311 to 320 of about 17,182,321 (391)

Asthma and stem cell therapy. [PDF]

World J Stem Cells
Chen QH, Zheng JY, Wang DC.
europepmc   +1 more source

Combined modality therapy for stage I–II large cell lymphoma

, 1987
Bradley R. Prestidgel, Sandra J. Horning, Richard T. Hoppe   +2 more
openalex   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

Enhancing the safety and efficacy of cell therapy with programmed sense-and-respond function. [PDF]

Clin Transl Med
Walters AJ, Yang X, Olson SD, Bashor CJ.
europepmc   +1 more source

A safe and potent anti-CD19 CAR T cell therapy

Nature Network Boston, 2019
Z. Ying, Xue F. Huang, X. Xiang, Yanling Liu, X. Kang, Yuqin Song, Xiao-tong Guo, Hanzhi Liu, N. Ding, Tingting Zhang, P. Duan, Yufu Lin, W. Zheng, Xiao-pei Wang, N. Lin, M. Tu, Yan Xie, Chen Zhang, Weiping Liu, L. Deng, Shunyu Gao, L. Ping, Xuejuan Wang, Nina Zhou, Junqing Zhang, Yulong Wang, Songfeng Lin, M. Mamuti, Xue-Zhong Yu, Lizhu Fang, Shuai Wang, Haifeng Song, Guan Wang, L. Jones, Jun Zhu, Si-Yi Chen   +35 more
semanticscholar   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Harnessing the promises of cell therapy, gene therapy, and regenerative medicine in Québec, Canada. [PDF]

Front Med (Lausanne)
Delisle JS, Fournier D, Santerre K, Rochette S, Zawati MH, Dumont-Lagacé M, Turcotte S, Guertin JR, Vermette P, Tremblay JP, Parisotto M, Beauséjour C, Petropoulos L, Kekre N, Michaud S, Dieudé M.   +15 more
europepmc   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Editorial: Immune cell therapy approaches targeting tumor microenvironment. [PDF]

Front Immunol
Patnaik SK, Kalathil SG.
europepmc   +1 more source

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li, David Liubart, Golam T. Saffi, Jonathan T. S. Chow, Ché M. P. Melo, Lydia To, Leonardo Salmena   +9 more
wiley   +1 more source