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Natural killer cell therapies
NatureNatural killer (NK) cells are lymphocytes of the innate immune system. A key feature of NK cells is their ability to recognize a wide range of cells in distress, particularly tumour cells and cells infected with viruses. They combine both direct effector functions against their cellular targets and participate in the generation, shaping and maintenance Vivier, Eric, Rebuffet, Lucas, Narni-Mancinelli, Emilie, Cornen, Stéphanie, Igarashi, Rob, Fantin, Valeria +5 moreopenaire +3 more sourceshPL-conditioned MSC-derived extracellular vesicles exhibit enhanced anticancer effects on MCF7 and A549 cells
Future Science OAIntroduction Mesenchymal stem cells (MSCs) have therapeutic potential due to their differentiation and immune-regulatory capabilities, mainly through the secretion of extracellular vesicles (EVs) which can exhibit pro- and anti-tumor effects.Aims This ...Nidaa A. Ababneh, Razan AlDiqs, Sura Nashwan, Mohammad A. Ismail, Raghda Barham, Fairouz Nairat, Enas Alwohoush, Shaymaa A. Hussein, Tareq Saleh, Abdalla Awidi +9 moredoaj +1 more sourceEAM conditioning regimen followed by autologous hematopoietic Stem Cell Transplantation for relapsed, refractory and high risk lymphomas
Mediterranean Journal of Hematology and Infectious Diseases, 2014 Hematopoietic Stem Cell Transplant is the standard treatment of refractory / recurrent lymphomas, most of conditioning regimens in this cases are BCNU-based as for BEAM & CBV , this agent (BCNU) is well-known for its severe lung toxicity .Mohamed BEKADJA, Tamim ALSULIMAN, Rachid BOUHASS, Abdessamed ARABI, Mohamed BRAHIMI, Soufi OSMANI, Nabil YAFOUR, Souad TALHI +7 moredoaj Article Commentary: First Human Myoblast Transfer Therapy Continues to Show Dystrophin after 6 Years
Cell Transplantation, 1997 Peter K. Law Ph.D., Tena G. Goodwin, Qiuwen Fang, Terry L. Hall, Tom Quinley, George Vastagh, Vijaya Duggirala, Charles Larkin, Jerry Ann Florendo, Lawrence Li, Tunja Jackson, T. J. Yoo, Nancy Chase, Michael Neel, Tim Krahn, Randall Holcomb +15 moredoaj +1 more sourceMyeloablative conditioning using timed-sequential busulfan plus fludarabine in older patients with acute myeloid leukemia: long-term results of a prospective phase II clinical trial
Haematologica, 2019 Rohtesh S. Mehta, Roland Bassett, Amanda Olson, Julianne Chen, Sairah Ahmed, Amin M. Alousi, Paolo Anderlini, Gheath Al-Atrash, Qaiser Bashir, Stefan O. Ciurea, Chitra M. Hosing, Jin S. Im, Partow Kebriaei, Issa Khouri, David Marin, Jeffrey J. Molldrem, Yago Nieto, Betul Oran, Katayoun Rezvani, Muzaffar H. Qazilbash, Samer A. Srour, Elizabeth J. Shpall, Borje S. Andersson, Richard E. Champlin, Uday R. Popat +24 moredoaj +1 more sourceScaling the manufacture of adipose tissue-derived mesenchymal stromal cells: integrated bioreactor workflows from inoculation to harvest without the need of seed train
BMC BiotechnologyBackground The production of human mesenchymal stromal cells (hMSC) for therapeutic use requires scalable, efficient and standardized manufacturing processes that could further benefit from shortening manufacturing time, automate and simplify operations ...Marta H. G. Costa, Ana Paula Terrasso, Inês E. Crespo, Raúl Valero, Beatriz Menéndez, Beatriz Painho, Carolina D. Sousa, Beatriz Gamelas, Hélio Tomás, Pablo Mancheno-Corvo, Ramón Menta, Carmen R. Gugel, Vanessa Fernández-Gómez, Ángel Herrero-Méndez, Irene Zamora Mármol, Alvaro Avivar-Valderas, Laura M. Pérez, Olga de la Rosa, Eleuterio Lombardo, Margarida Serra, Maitane Ortiz-Virumbrales +20 moredoaj +1 more source
