Results 81 to 90 of about 6,961,378 (302)

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Analyzing the complex machinery of cell wall biosynthesis [PDF]

open access: yes, 2009
The plant cell wall polymers make up most of the plant biomass and provide the raw material for many economically important products including food, feed, bio-materials, chemicals, textiles, and biofuel.
Timmers, J.F.P.
core  

Chemically Induced Cell Wall Stapling in Bacteria

open access: yes, 2021
Transpeptidation reinforces the structure of cell-wall peptidoglycan, an extracellular heteropolymer that protects bacteria from osmotic lysis. The clinical success of transpeptidase-inhibiting beta-lactam antibiotics illustrates the essentiality of ...
Aditham, Arjun K.   +7 more
core   +1 more source

Scaffolding of long read assemblies using long range contact information

open access: yesBMC Genomics, 2017
Background Long read technologies have revolutionized de novo genome assembly by generating contigs orders of magnitude longer than that of short read assemblies.
Jay Ghurye   +4 more
doaj   +1 more source

Endopeptidase-mediated beta lactam tolerance. [PDF]

open access: yesPLoS Pathogens, 2015
In many bacteria, inhibition of cell wall synthesis leads to cell death and lysis. The pathways and enzymes that mediate cell lysis after exposure to cell wall-acting antibiotics (e.g.
Tobias Dörr   +2 more
doaj   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

Staphylococcus aureus: salt stress, cell wall deficiency, and Biofílm formation [PDF]

open access: yes, 2008
Staphylococcus aureus (S. aureus) is a major cause of chronic infection and is of particular concern in the infection of implanted prostheses. Biofilm formation offers bacteria innate protection from antimicrobial agents and prevents the eradication of ...
Beckingsale, Thomas
core  

Phage display-derived inhibitor of the essential cell wall biosynthesis enzyme MurF [PDF]

open access: yes, 2008
Background To develop antibacterial agents having novel modes of action against bacterial cell wall biosynthesis, we targeted the essential MurF enzyme of the antibiotic resistant pathogen Pseudomonas aeruginosa.
Sanschagrin, François   +13 more
core   +1 more source

Impact of Fungal MAPK Pathway Targets on the Cell Wall

open access: yesJournal of Fungi, 2018
The fungal cell wall is an extracellular organelle that provides structure and protection to cells. The cell wall also influences the interactions of cells with each other and surfaces.
Jacky Chow   +4 more
doaj   +1 more source

Bacterial cell wall composition and the influence of antibiotics by cell-wall and whole-cell NMR [PDF]

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2015
The ability to characterize bacterial cell-wall composition and structure is crucial to understanding the function of the bacterial cell wall, determining drug modes of action and developing new-generation therapeutics. Solid-state NMR has emerged as a powerful tool to quantify chemical composition and to map cell-wall architecture
Joseph A H, Romaniuk, Lynette, Cegelski
openaire   +2 more sources

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