Results 101 to 110 of about 20,584 (339)

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

open access: yesAdvanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang   +16 more
wiley   +1 more source

Wine Cellar Management Tool, Version 3.1.0.

open access: yes, 2016
Version 3 of the Wine Cellar Management Tool incorporates six years of experience in using this spreadsheet-based application, which is designed to assist a wine owner in tracking the status of bottles being cellared.
Thompson, Gary
core  

DEVELOPMENT OF SELECTED PARAMETERS OF MICROCLIMATE IN A STAND ALONE CELLAR PLUNGED INTO SOIL

open access: yes, 2017
The thesis presents the analysis of development of selected parameters of microclimate in a standalone cellar plunged into soil. The scope of studies included measurement of air internal and external temperature and relative humidity of internal and ...
G. Nawalany   +3 more
semanticscholar   +1 more source

A 3D In Vitro Model of the Human Hepatobiliary Junction

open access: yesAdvanced Science, EarlyView.
A 3D human organoid platform reconstructs the hepatobiliary junction between primary adult hepatocytes and intrahepatic cholangiocytes. These adult hepatobiliary organoids (aHBOs) support directional bile transport from canaliculi to ductule‐like structures, enable quantitative imaging of junction dynamics, and reveal cell‐type‐specific vulnerabilities
Ashley D. Westerfield   +13 more
wiley   +1 more source

cellar lath cellar laths cellar lats

open access: yes, 1973
cellar lath[PT] I sharpened th' axe...., poor ol' father chopped some cellar lats, cellar studs.... (could be mistake, corrected as _cellar studs)YesDNE-cit DNE-citJ.D.A.WIDDOWSON AUG 1973Not usedNot usedWithdrawnChecked by Jordyn Hughes on Thu 14 ...

core  

NIBV Induces Incomplete Autophagy via AMPK‐TFEB, Causing Kidney Injury in Chicks

open access: yesAdvanced Science, EarlyView.
This study reveals that NIBV can inhibit the nuclear translocation of TFEB by suppressing the expression of AMPK, leading to the blockade of autophagolysosomal functions, in turn increasing NIBV replication and triggering severe kidney injury in chicks.
Cheng Huang   +10 more
wiley   +1 more source

cellar stud cellar studs

open access: yes, 1973
cellar stud[PT] I sharpened th' axe...., poor ol' father chopped some cellar lats, cellar studs....YesJ.D.A.WIDDOWSON AUG 1973Not usedNot usedWithdrawnChecked by Jordyn Hughes on Thu 14 Jul ...

core  

Mechanostimulatory Cues Determine Intestinal Fibroblast Fate and Profibrotic Remodeling in a Physiodynamic Human Gut‐on‐a‐Chip

open access: yesAdvanced Science, EarlyView.
A healthy gut barrier shields underlying fibroblasts from luminal shear forces, illustrating that “good fences make good neighbors.” Barrier damage exposes fibroblasts to shear stress, inducing cell death and the emergence of stress‐adapted, profibrotic fibroblasts. Sustained shear exposure promotes the formation of stiff aggregates of mechanoadapative
Soyoun Min   +6 more
wiley   +1 more source

Design of Sustainable Agricultural Buildings. A Case Study of a Wine Cellar in Tuscany, Italy

open access: yes, 2016
This research concerns the design of an agricultural building with a high degree of sustainability, located in a farm in the south of the Tuscany region, Italy.
L. Conti, M. Barbari, Massimo Monti
semanticscholar   +1 more source

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

open access: yesAdvanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang   +32 more
wiley   +1 more source

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