Results 171 to 180 of about 12,756,677 (346)

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Effect of Electrical Stimulation on PC12 Cells Cultured in Different Hydrogels: Basis for the Development of Biomaterials in Peripheral Nerve Tissue Engineering. [PDF]

Pharmaceutics, 2023
Olguín Y, Selva M, Benavente D, Orellana N, Montenegro I, Madrid A, Jaramillo-Pinto D, Otero MC, Corrales TP, Acevedo CA.   +9 more
europepmc   +1 more source

Propagation of prions causing synucleinopathies in cultured cells

Proceedings of the National Academy of Sciences of the United States of America, 2015
A. Woerman, J. Stöhr, A. Aoyagi, R. Rampersaud, Zuzana Krejciova, J. Watts, T. Ohyama, Smita Patel, Kartika Widjaja, Abby Oehler, David W. Sanders, M. Diamond, W. Seeley, L. Middleton, S. Gentleman, Daniel A Mordes, T. Südhof, K. Giles, S. Prusiner   +18 more
semanticscholar   +1 more source

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

Molecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef, Hana Barhom, Sumit Chatterji, Netta Hecht, Oran Warhaftig, Iris Kamer, Oranit Zadok, Jair Bar, Limor Broday, Amir Onn, Michael Peled   +10 more
wiley   +1 more source

The primary study on the application of gelatum invasive model as an invasiveness assay for glioma cells in vitro

Chinese Journal of Contemporary Neurology and Neurosurgery, 2010
Objective To investigate the feasibility of applying gelatum invasive model as an invasiveness assay for human glioma cells in vitro, observe the differences of invasiveness between adherently cultured differentiated human glioma cells and human glioma ...
Rui⁃fan XIE, Suo⁃jun ZHANG, Bao⁃cheng GAO, Feng WAN, Ting LEI   +4 more
doaj  

Saos-2 cells cultured under hypoxia rapidly differentiate to an osteocyte-like stage and support intracellular infection by Staphylococcus aureus. [PDF]

Physiol Rep, 2023
Zelmer AR, Starczak Y, Solomon LB, Richter K, Yang D, Atkins GJ.   +5 more
europepmc   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Measurement of superoxide dismutase, catalase and glutathione peroxidase in cultured cells and tissue

Nature Protocols, 2010
C. Weydert, J. Cullen
semanticscholar   +1 more source

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

Molecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo, Yoshihiro Mezawa, Zixu Wang, Ahmet Acar, Yasuhiko Ito, Atsushi Takano, Yohei Miyagi, Tomoyuki Yokose, Yamashita Toshinari, Yataro Daigo, Takuya Shirakihara, Akira Orimo   +11 more
wiley   +1 more source

Analysis of the expression of normal and mutant full⁃length atrophin⁃1 gene in stable and transient transfected eukaryotic cell line

Chinese Journal of Contemporary Neurology and Neurosurgery, 2011
Objective To establish eukaryotic expression system of full ⁃ length gene in normal [CAG repeats (Q19)] and abnormal [CAG repeats (Q82 and Q66)] atrophin ⁃ 1 [the pathogenic gene of dentatorubral⁃pallidoluysian atrophy (DRPLA)]. To compare the expression
Xin ZHANG, Weihong GU, Guoxiang WANG
doaj