Results 11 to 20 of about 25,291,875 (362)
TIMER2.0 for analysis of tumor-infiltrating immune cells
Nucleic Acids Res., 2020 Tumor progression and the efficacy of immunotherapy are strongly influenced by the composition and abundance of immune cells in the tumor microenvironment.
Taiwen Li +7 more
semanticscholar +1 more source
Generating heterokaryotic cells via bacterial cell-cell fusion [PDF]
Microbiology Spectrum, 2021 Cell-cell fusion is fundamentally important for tissue repair, virus transmission, and genetic recombination, among other functions. Fusion has been mainly studied in eukaryotic cells and lipid vesicles, while cell-cell fusion in bacteria is less well characterized, due to the cell wall acting as a fusion-limiting barrier.
Shitut, S.S. +7 more
openaire +5 more sources
Engineering cell–cell signaling [PDF]
Current Opinion in Biotechnology, 2013 Juxtacrine cell-cell signaling mediated by the direct interaction of adjoining mammalian cells is arguably the mode of cell communication that is most recalcitrant to engineering. Overcoming this challenge is crucial for progress in biomedical applications, such as tissue engineering, regenerative medicine, immune system engineering and therapeutic ...
Katarina, Blagovic +4 more
openaire +2 more sources
Neurodegeneration cell per cell
Neuron, 2023 The clinical definition of neurodegenerative diseases is based on symptoms that reflect terminal damage of specific brain regions. This is misleading as it tells little about the initial disease processes. Circuitry failures that underlie the clinical symptomatology are themselves preceded by clinically mostly silent, slowly progressing multicellular ...
Balusu, Sriram +4 more
openaire +4 more sources
Massively parallel digital transcriptional profiling of single cells
Nature Communications, 2016 Characterizing the transcriptome of individual cells is fundamental to understanding complex biological systems. We describe a droplet-based system that enables 3′ mRNA counting of tens of thousands of single cells per sample.
semanticscholar +1 more source
Survey of Ophthalmology, 2007 A 64-year-old woman presented with bilateral optic nerve swelling, vitreous cells, and cerebrospinal fluid monocytic pleocytosis. A chest radiograph and computed tomography demonstrated a lesion in the left lung, which histologically was confirmed to be a small-cell lung carcinoma.
Departments of Ophthalmology and Medicine (Division of Neurology), Duke University Eye Center and Duke University Medical Center, Durham, North Carolina ( host institution ) +4 more
openaire +3 more sources
FEBS Letters, 2007 Cell–cell fusion is a highly regulated and dramatic cellular event that is required for development and homeostasis. Fusion may also play a role in the development of cancer and in tissue repair by stem cells. While virus–cell fusion and the fusion of intracellular membranes have been the subject of intense investigation during the past decade, cell ...
Chen, Elizabeth H. +3 more
openaire +2 more sources
Revised Estimates for the Number of Human and Bacteria Cells in the Body
bioRxiv, 2016 We critically revisit the “common knowledge” that bacteria outnumber human cells by a ratio of at least 10:1 in the human body. We found the total number of bacteria in the “reference man” to be 3.9·1013, with an uncertainty (SEM) of 25%, and a variation
R. Sender, Shai Fuchs, R. Milo
semanticscholar +1 more source
Controlling Synthetic Cell-Cell Communication [PDF]
Frontiers in Molecular Biosciences, 2022 Synthetic cells, which mimic cellular function within a minimal compartment, are finding wide application, for instance in studying cellular communication and as delivery devices to living cells. However, to fully realise the potential of synthetic cells, control of their function is vital.
Smith, J, Chowdhry, R, Booth, M
openaire +4 more sources
Phenotypic characterization of human prostatic stromal cells in primary cultures derived from human tissue samples [PDF]
, 2013 Emerging evidence has shown that the tumor microenvironment plays a crucial role in prostate cancer (PCa) development and progression. However, the mechanism(s) through which stromal cells regulate epithelial cells and the differences among prostatic ...
Clemente, Luigi Di +7 more
core +1 more source