Results 241 to 250 of about 10,304,224 (308)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Retracted: Effect of Fas and Bcl-2 DNA Damages Response Expression in Stem Cells on Apoptosis of Nucleus Pulposus of Intervertebral Disc

Stem Cells International
Stem Cells International
doaj   +1 more source

TCR-JANUS engager proteins enable bispecific targeting to overcome tumor heterogeneity in TCR-T cell therapy. [PDF]

Sci Adv
Cheng C, Liang T, Yao P, Wang W, Chen H, Li X, Tian Y, Wang J, Yan N, Xie D, Qiu F, Tan S.   +11 more
europepmc   +1 more source

Retracted: Human Umbilical Mesenchymal Stem Cells-Derived Microvesicles Attenuate Formation of Hypertrophic Scar through Multiple Mechanisms

Stem Cells International
Stem Cells International
doaj   +1 more source

Retracted: Loading Gentamicin and Zn2+ on TiO2 Nanotubes to Improve Anticoagulation, Endothelial Cell Growth, and Antibacterial Activities

Stem Cells International
Stem Cells International
doaj   +1 more source

Role of Rab4A in the enhancement of cancer cell invasion induced by plasma samples collected during radiotherapy in patients with triple-negative breast cancer. [PDF]

PLoS One
Paquette B, Therriault H, Gauthier I, Provencher S, Bourque JM, Naasri S, Oweida A, Geha S, Labrecque P, Parent JL.   +9 more
europepmc   +1 more source

Resveratrol mitigates hypoxia-induced mitochondrial oxidative damage and apoptosis <i>via</i> inhibition of TRPA1 channel in retinal pigment epithelial cells. [PDF]

Int J Ophthalmol
Argun M, Nazıroğlu M.
europepmc   +1 more source

Retracted: Nucleus Pulposus Cells Induce M2 Polarization of RAW264.7 via CX3CL1/CX3CR1 Pathway and M2 Macrophages Promote Proliferation and Anabolism of Nucleus Pulposus Cells

Stem Cells International
Stem Cells International
doaj   +1 more source