Results 61 to 70 of about 25,291,875 (362)

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Transfer cells [PDF]

open access: yesFrontiers in Plant Science, 2014
Transfer cells are anatomically specialized cells optimized to support high levels of nutrient transport in plants. These cells trans-differentiate from existing cell types by developing extensive and localized wall ingrowth labyrinths to amplify plasma membrane surface area which in turn supports high densities of membrane transporters. Unsurprisingly,
McCurdy, David, Hueros, Gregorio
openaire   +5 more sources

Extracellular vesicles transfer nuclear Abl-dependent and radiation-induced miR-34c into unirradiated cells to cause bystander effects. [PDF]

open access: yes, 2018
Ionizing radiation (IR) not only activates DNA damage response (DDR) in irradiated cells but also induces bystander effects (BE) in cells not directly targeted by radiation.
Chan, Josolyn   +3 more
core  

Cell Sorting daring Pattern Formation in Dictyostelium [PDF]

open access: yes, 1981
Formation of the prestalk-prespore pattern in Dictyostelium was investigated in slugs and submerged clumps of cells. Prestalk and prespore cells were identified by staining with vital dyes, which are shown to be stable cell markers.
David, Charles N., Sternfeld, John
core   +1 more source

Immunobiology of dendritic cells.

open access: yesAnnual Review of Immunology, 2000
Dendritic cells (DCs) are antigen-presenting cells with a unique ability to induce primary immune responses. DCs capture and transfer information from the outside world to the cells of the adaptive immune system.
J. Banchereau   +7 more
semanticscholar   +1 more source

Celles [PDF]

open access: yesADLFI. Archéologie de la France - Informations, 2006
Identifiant de l'operation archeologique : 113 Date de l'operation : 2005 (FP) Le site dit du tumulus de Celles pose, depuis sa date de decouverte au tout debut du XXe s. par l’archeologue cantalien Jean Pages‑Allary, une serie de questionnements qui touchent a : – la definition exacte de sa fonction ; – la chronologie precise d’occupation du site ...
Izac-Imbert, Lionel, Izac-Imbert, Lionel
openaire   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman   +8 more
wiley   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul   +13 more
wiley   +1 more source

Positive selection determines T cell receptor V beta 14 gene usage by CD8+ T cells. [PDF]

open access: yes, 1989
We report here a mAb, 14-2, reactive with TCRs that include V beta 14. The frequency of V beta 14+ T cells varies with CD4 and CD8 subset and is controlled by the H-2 genes.
Liao, N, Maltzman, J, RAULET, David H.
core  

Functional characterization of reappearing B cells after anti-CD20 treatment of CNS autoimmune disease. [PDF]

open access: yes, 2018
The anti-CD20 antibody ocrelizumab, approved for treatment of multiple sclerosis, leads to rapid elimination of B cells from the blood. The extent of B cell depletion and kinetics of their recovery in different immune compartments is largely unknown ...
Bernard, Claude CA   +9 more
core   +1 more source

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