Results 11 to 20 of about 344,382 (120)
Parasitoids exploit host bodies for reproduction, selecting for host defences. A new host defence is reported, in which adult Drosophila accelerate mating behaviour at the sight of certain parasitoid wasps, mediated by the upregulation of a nervous ...
Shimaa A. M. Ebrahim +2 more
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XPO5 promotes primary miRNA processing independently of RanGTP
XPO5 mediates nuclear export of miRNA hairpin precursors (pre-miRNAs) through a RanGTP-dependent binding. Here the authors employ HITS-CLIP and biochemical analysis and show that XPO5 binds and promotes nuclear processing of clustered pri-miRNAs, with ...
Jingjing Wang +6 more
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Non‐genetic diversity modulates population performance
Biological functions are typically performed by groups of cells that express predominantly the same genes, yet display a continuum of phenotypes. While it is known how one genotype can generate such non‐genetic diversity, it remains unclear how different
Adam James Waite +5 more
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Noise reduction as an emergent property of single-cell aging
Gene expression is a noisy process, but it is not known how noise in gene expression changes during the aging of single cells. Here the authors show that noise decreases during normal aging, and provide support for aging-associated increases in chromatin
Ping Liu +4 more
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Synthetic cargo adaptors reveal molecular features that enhance dynein activation
Cytoplasmic dynein-1 (dynein) facilitates the microtubule-based retrograde trafficking of all cellular cargo. To become active, dynein binds dynactin and one of many cargo-specific adaptors forming the dynein-dynactin-adaptor transport complex.
Aravintha Siva +10 more
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Spatial self-organization resolves conflicts between individuality and collective migration
How bacteria migrate collectively despite individual phenotypic variation is not understood. Here, the authors show that cells spontaneously sort themselves within moving bands such that variations in individual tumble bias, a determinant of gradient ...
X. Fu +7 more
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Sis2 regulates yeast replicative lifespan in a dose-dependent manner
Application of microfluidic platforms facilitated high-precision measurements of yeast replicative lifespan (RLS); however, comparative quantification of lifespan across strain libraries has been missing.
Tolga T. Ölmez +7 more
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An efficient multiplex approach to CRISPR/Cas9 gene editing in citrus
CRISPR/Cas9-mediated gene editing requires high efficiency to be routinely implemented, especially in species which are laborious and slow to transform. This requirement intensifies further when targeting multiple genes simultaneously, which is required ...
Cintia H. D. Sagawa +6 more
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An extracellular matrix of Fibronectin adheres the neural tube to the two flanking columns of paraxial mesoderm and is required for normal vertebrate development.
Emilie Guillon +5 more
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The current state and limitations of research on extracellular vesicles in central nervous system (CNS) signaling are discussed, with particular focus on EV-mediated cargo transfer.
Chun Wan +2 more
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