Results 61 to 70 of about 16,736 (251)

Cell-autonomous regulation of epithelial cell quiescence by calcium channel Trpv6

eLife, 2019
Epithelial homeostasis and regeneration require a pool of quiescent cells. How the quiescent cells are established and maintained is poorly understood. Here, we report that Trpv6, a cation channel responsible for epithelial Ca2+ absorption, functions as ...
Yi Xin, Allison Malick, Meiqin Hu, Chengdong Liu, Heya Batah, Haoxing Xu, Cunming Duan   +6 more
doaj   +1 more source

The E3 ligase Riplet promotes RIG-I signaling independent of RIG-I oligomerization

Nature Communications, 2023
RIG-I is an essential innate immune receptor that responds to infection by RNA viruses. The RIG-I signaling cascade is mediated by a series of post-translational modifications, the most important of which is ubiquitination of the RIG-I Caspase ...
Wenshuai Wang, Benjamin Götte, Rong Guo, Anna Marie Pyle   +3 more
doaj   +1 more source

A proposed design for the cryopreservation of intact and adherent human embryonic stem cell colonies

, 2005
10.1290/04090651.1In Vitro Cellular and Developmental Biology - Animal413-477 ...
Heng, B.C., Chan, S.H., Cao, T., Bested, S.M.   +3 more
core   +1 more source

Of Mice and Women: A Comparative Tissue Biology Perspective of Breast Stem Cells and Differentiation [PDF]

, 2015
Tissue based research requires a background in human and veterinary pathology, developmental biology, anatomy, as well as molecular and cellular biology.
Gabriela Dontu, Dontu, Gabriela, Ince, Tan A, Tan A. Ince   +3 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

A dedicated skin-to-brain circuit for cool sensation in mice

Nature Communications
Perception of external temperature is essential for maintaining homeostasis and avoiding thermal injury. Although molecular thermosensors such as transient receptor potential melastatin type 8 (TRPM8) have been identified, the neural circuits responsible
Hankyu Lee, Chia Chun Hor, Lorraine R. Horwitz, Ailin Xiong, Xin-Yu Su, Daniel R. Soden, Sarah Yang, Wei Cai, Wenwen Zhang, Chen Li, Christopher Radcliff, Abbey Dinh, Tin Long Rex Fung, Ilma Rovcanin, Kevin P. Pipe, X. Z. Shawn Xu, Bo Duan   +16 more
doaj   +1 more source

Feeder cell density - A key parameter in human embryonic stem cell culture

, 2004
10.1290/0407052.1In Vitro Cellular and Developmental Biology - Animal408-9255 ...
Heng, B.C., Cao, T., Liu, H.
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Human embryonic stem cell (hES) colonies display a higher degree of spontaneous differentiation when passaged at lower densities

, 2006
10.1290/0510071.1In Vitro Cellular and Developmental Biology - Animal423-454 ...
Heng, B.C., Rufaihah, A.J., Cao, T., Liu, H.   +3 more
core   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source