Results 101 to 110 of about 359,726 (298)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

The extracellular matrix of plants: Molecular, cellular and developmental biology [PDF]

, 1996
A symposium entitled ``The Extracellular Matrix of Plants: Molecular, Cellular and Developmental Biology was held in Tamarron, Colorado, March 15--21, 1996.

core  

There is more than one way to turn a spherical cellular monolayer inside out: type B embryo inversion in Volvox globator [PDF]

, 2011
Höhn S, Hallmann A. There is more than one way to turn a spherical cellular monolayer inside out: type B embryo inversion in Volvox globator. BMC Biology.
Höhn Stephanie, Hallmann Armin, Höhn, Stephanie, Hallmann, Armin ; https://orcid.org/, Armin Hallmann, Stephanie Höhn   +5 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Identification and expression of voltage-gated calcium channel Β subunits in Zebrafish [PDF]

, 2008
Voltage-gated calcium channels (VGCC) play important roles in electrically excitable cells and embryonic development. The VGCC Β subunits are essential for membrane localization of the channel and exert modulatory effects on channel functions. In mammals,
John Y. Kuwada, Hiromi Hirata, Eric James Horstick, Hirata, Hiromi, Kuwada, John Y., Zhou, Weibin, Horstick, Eric James, Weibin Zhou   +7 more
core   +1 more source

Single-cell mapping of lipid metabolites using an infrared probe in human-derived model systems

Nature Communications
Understanding metabolic heterogeneity is the key to uncovering the underlying mechanisms of metabolic-related diseases. Current metabolic imaging studies suffer from limitations including low resolution and specificity, and the model systems utilized ...
Yeran Bai, Carolina M. Camargo, Stella M. K. Glasauer, Raymond Gifford, Xinran Tian, Andrew P. Longhini, Kenneth S. Kosik   +6 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Echinoderms : Focus on the Sea Urchin Model in Cellular and Developmental Biology

, 2021
Echinoderms, a sister group of chordates, is a group of exclusively marine animals. TheEchinodermata is an ancient phylum dating to at least 450 million years old and includingmore than 10,000 extant species present throughout the world’s oceans. The modernechinoderms belong to five classes: Echinoidea (e.g., sea urchins and sand dollars),Asteroidea (e.
Pontheaux, Florian, Roch, Fernando, Morales, Julia, Cormier, Patrick   +3 more
openaire   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source