Results 41 to 50 of about 7,019 (311)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Probabilistic cellular automata for interacting fermionic quantum field theories

open access: yesNuclear Physics B, 2021
A classical local cellular automaton can describe an interacting quantum field theory for fermions. We construct a simple classical automaton for a particular version of the Thirring model with imaginary coupling. This interacting fermionic quantum field
C. Wetterich
doaj   +1 more source

Cellular Automaton Supercomputing [PDF]

open access: yes, 2018
Many of the models now used in science and engineering are over a century old. And most of them can be implemented on modern digital computers only with considerable difficulty. Some new basic models are discussed which are much more directly suitable for digital computer simulation. The fundamental principle is that the models considered herein are as
openaire   +1 more source

Number-conserving cellular automaton rules

open access: yes, 1999
A necessary and sufficient condition for a one-dimensional q-state n-input cellular automaton rule to be number-conserving is established. Two different forms of simpler and more visual representations of these rules are given, and their flow diagrams are determined. Various examples are presented and applications to car traffic are indicated.
Boccara, N., Fuk'S, H.
openaire   +4 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Learning About Growing Neural Cellular Automata

open access: yesIEEE Access
Neural cellular automata have been proven effective in simulating morphogenetic processes. Developing such automata has been applied in 2D and 3D processes related to creating and regenerating complex structures and enabling their behaviors.
Sorana Catrina   +3 more
doaj   +1 more source

A crowd route choice evacuation model in large indoor building spaces

open access: yesFrontiers of Architectural Research, 2018
Route choice is a fundamental requirement in the evacuation process. The aim of this paper is to identify a method to simulate crowds in large indoor spaces with consideration of the acoustic system.
Y. Wu, J. Kang, C. Wang
doaj   +1 more source

The Cellular Automaton [PDF]

open access: yes, 2016
A time-reversible cellular automaton can most easily be described by regarding its evolution law as a two-step process, for instance by first allowing the even sites to update, then the odd sites. The discrete Hamiltonian operator procedure of Chap. 19 may be used.
openaire   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

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