Results 61 to 70 of about 864,406 (289)

A low-cost alternative method of generating fibronectin micropatterned lines for cellular applications

open access: yesMethodsX, 2023
The cellular microenvironment contributes to the architecture, differentiation, polarity, mechanics and functions of the cell [1]. Spatial confinement of cells using micropatterning techniques allows to alter and regulate the cellular microenvironment ...
Johanna Elisabeth Becher   +2 more
doaj   +1 more source

Glioma through the looking GLASS: molecular evolution of diffuse gliomas and the Glioma Longitudinal Analysis Consortium. [PDF]

open access: yes, 2018
Adult diffuse gliomas are a diverse group of brain neoplasms that inflict a high emotional toll on patients and their families. The Cancer Genome Atlas and similar projects have provided a comprehensive understanding of the somatic alterations and ...
GLASS Consortium
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Lightweight reflector assembly [PDF]

open access: yes, 1977
An inexpensive, lightweight reflective assembly member having good optical quality and particularly adaptable to accommodating temperature variations without providing destructive thermal stresses and reflective slope errors is described.
Argoud, M. J., Jolley, J., Walker, W. L.
core   +1 more source

Diversification of a protein kinase cascade: IME-2 is involved in nonself recognition and programmed cell death in Neurospora crassa. [PDF]

open access: yes, 2012
Kinase cascades and the modification of proteins by phosphorylation are major mechanisms for cell signaling and communication, and evolution of these signaling pathways can contribute to new developmental or environmental response pathways.
Bueche, Joanna A   +2 more
core   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

CELLULAR GLASS FROM POST-CONSUMER DRINKING GLASS NON-CONVENTIONALLY PREPARED WITH SILICON NITRIDE AND MANGANESE DIOXIDE AS PORE-FORMING AGENTS

open access: yesNonconventional Technologies Review, 2023
Cellular glass non-conventionally prepared from post-consumer drinking glass was made, silicon nitride (Si3N4) and manganese dioxide (MnO2) contributing to form the porous structure.
Lucian Paunescu   +2 more
doaj  

Glass Microspheres Thermo-Deformation Sintering Processes in the Technologies of Obtaining Materials for Underwater Technical Equipment

open access: yesPolish Maritime Research, 2023
In this work, the important scientific and technical problem of creating multifunctional composite materials for shipbuilding and ocean engineering was solved.
Kazymyrenko Yuliia   +2 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Effects of carbon nanotubes/graphene nanoplatelets hybrid systems on the structure and properties of polyetherimide-based foams [PDF]

open access: yes, 2018
Foams based on polyetherimide (PEI) with carbon nanotubes (CNT) and PEI with graphene nanoplatelets (GnP) combined with CNT were prepared by water vapor induced phase separation. Prior to foaming, variable amounts of only CNT(0.1–2.0wt%) or a combination
Abbasi, Hooman   +2 more
core   +3 more sources

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