Results 131 to 140 of about 2,435,187 (246)

Enabling community-based autologous adaptive immune cellular therapy manufactured at the point of care: A narrative review of global regulatory frameworks, affordability, and implementation strategy of a novel integrated facility and digital platform in the United States. [PDF]

Transfusion
Dixon RB, Warin R, Montague J, Austin A, Powderly JD.   +4 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Transduction efficiency in clinical CAR T cell products: A retrospective study at a single center. [PDF]

Mol Ther Adv
Shao L, Prochazkova M, Cai Y, Lee Han K, Martin K, Shi R, Yang R, Ma J, Zheng Y, Garces P, Frodigh SE, Pham V, Zhang N, Somerville RP, Stroncek DF, Jin P.   +15 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Recent Advances in High-Performance Bioinspired Sustainable Materials for Automotive Applications. [PDF]

Materials (Basel)
Kumari K, Pradhan S, Mishra M, Barua A, Samantra C, Rout T, Priyadarshini M.   +6 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Jeffrey Manufacturing Company mortar mixer photograph

, 1899
This photograph depicts a one-horsepower mortar mixer used during the construction of a factory building at the Jeffrey Manufacturing Company in Columbus, Ohio. Steel paddles on a long shaft in the trough were turned by the horse to mix the cement mortar.
The Jeffrey Manufacturing Company (Photographer)
core  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Jeffrey Manufacturing Company Water Tower

, 1960
This is a photograph of the Jeffrey Manufacturing Company water tower in Columbus, Ohio, ca. 1960 - 1970.
The Jeffrey Manufacturing Company (Photographer)
core  

Beyond printing: toward biologically informed biofabrication. [PDF]

Front Bioeng Biotechnol
Motta A.
europepmc   +1 more source