Results 41 to 50 of about 4,958,442 (285)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Pseudo almost automorphic solutions of quaternion-valued neural networks with infinitely distributed delays via a non-decomposing method

Advances in Difference Equations, 2019
In this paper, we consider the existence and global exponential stability of pseudo almost automorphic solutions to quaternion-valued cellular neural networks with infinitely distributed delays.
Jianglian Xiang, Yongkun Li
doaj   +1 more source

Cardiolipin’s Remodeling Rules Revealed: The Role of the Cellular Lipidome

Cell Reports, 2020
In this issue of Cell Reports, Oemer et al. (2020) define the acyl chain composition of cardiolipin and other lipid classes in murine tissues. They then employ artificial neural networks to predict mechanisms that govern cardiolipin tissue specificity ...
Olivia L. Sniezek, Arianna F. Anzmann, Steven M. Claypool, Hilary J. Vernon   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Fixed-Time Synchronization for Fractional-Order Cellular Inertial Fuzzy Neural Networks with Mixed Time-Varying Delays

Fractal and Fractional
Due to the widespread application of neural networks (NNs), and considering the respective advantages of fractional calculus (FC), inertial neural networks (INNs), cellular neural networks (CNNs), and fuzzy neural networks (FNNs), this paper investigates
Yeguo Sun, Yihong Liu, Lei Liu
doaj   +1 more source

Convolutional Neural Network-Based Artificial Intelligence for Classification of Protein Localization Patterns

Biomolecules, 2021
Identifying localization of proteins and their specific subpopulations associated with certain cellular compartments is crucial for understanding protein function and interactions with other macromolecules. Fluorescence microscopy is a powerful method to
Kaisa Liimatainen, Riku Huttunen, Leena Latonen, Pekka Ruusuvuori   +3 more
doaj   +1 more source

Cellular neural networks, Navier-Stokes equation and microarray image reconstruction [PDF]

, 2011
Copyright @ 2011 IEEE.Although the last decade has witnessed a great deal of improvements achieved for the microarray technology, many major developments in all the main stages of this technology, including image processing, are still needed.
Bachar Zineddin, Zineddin, B, Liu, X, Wang, Z, null Zidong Wang, null Xiaohui Liu   +5 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

A Novel Algorithm for Generating Pseudo-Random Number

International Journal of Computational Intelligence Systems, 2019
It proposes a pseudo-random number generation algorithm based on cellular neural networks. This method uses the hyper-chaos characteristics of the cellular neural networks and sets the appropriate parameters to generate the pseudo-random number.
Gangyi Hu, Jin Peng, Weili Kou
doaj   +1 more source