Results 71 to 80 of about 3,960,239 (293)

Using machine learning models to predict the impact of template mismatches on polymerase chain reaction assay performance

Scientific Reports
Molecular assays are critical tools for the diagnosis of infectious diseases. These assays have been extremely valuable during the COVID pandemic, used to guide both patient management and infection control strategies.
Brittany Knight, Taylor Otwell, Michael P. Coryell, Jennifer Stone, Phillip Davis, Bryan Necciai, Paul E. Carlson, Shanmuga Sozhamannan, Alyxandria M. Schubert, Yi H. Yan   +9 more
doaj   +1 more source

Cytokeratin expression in breast cancer: from mechanisms, progression, diagnosis, and prognosis to therapeutic implications

Molecular & Cellular Oncology
Background and Aim Cytokeratins (CKs) are structural proteins vital to epithelial integrity and play key roles in breast cancer progression. This review explores their expression, functions, and therapeutic potential.Methods A systematic review was ...
Ensiyeh Bahadoran, Sahar Moghbelinejad, Ghazaleh Mohammadi, Hamid Shahbazmohammadi, Zohreh Abdolvahabi, Manijeh Jalilvand, Isareza Zare, Masood Alaei, Sanaz Keshavarz Shahbaz   +8 more
doaj   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Respecting children: annual report of the Ombudsman for Children's Office, April 2005 - December 2006 [PDF]

, 2007
Ombudsman for Children's Office ...
Ombudsman for Children Office (OCO)
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Personal property at the Oak Ridge Operations Office and the Office of Scientific and Technical Information [PDF]

, 1998
The Oak Ridge Operations Office (Operations Office) and the Office of Scientific and Technical Information (OSTI) are responsible for safeguarding and controlling personal property in their possession and in the possession of their contractors ...

core   +1 more source

Functional characterization of Francisella tularensis subspecies holarctica genotypes during tick cell and macrophage infections using a proteogenomic approach

Frontiers in Cellular and Infection Microbiology
Tularemia is a vector-borne disease caused by the Gram-negative bacterium Francisella tularensis. Known hosts and vectors in Europe are hare and ticks. F.
Sara Doina Schütz, Sara Doina Schütz, Sara Doina Schütz, Maximilian Brackmann, Nicole Liechti, Michel Moser, Matthias Wittwer, Rémy Bruggmann   +7 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Hypoglycemia compensation mechanisms in dry fasting

Metabolism Open
Background: Dry fasting (DF) presents three primary risks: hypovolemia, hypertonicity, and hypoglycemia. The first two have been shown to be effectively compensated, and the respective mechanisms have been studied.
Ioannis-Eleemon Papagiannopoulos-Vatopaidinos, Maria I. Papagiannopoulou, Eleni N. Dotsika   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Annual report 2004 - Office of Tobacco Control

, 2005
Office of Tobacco Control ...
Office of Tobacco Control
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