Results 161 to 170 of about 114,739 (248)

Intermediate cells of in vitro cellular reprogramming and in vivo tissue regeneration require desmoplakin. [PDF]

open access: yesSci Adv, 2022
Ha J   +22 more
europepmc   +1 more source

Warming Induces Significant Reprogramming of Beige, but Not Brown, Adipocyte Cellular Identity [PDF]

open access: bronze, 2018
Hyun Cheol Roh   +10 more
openalex   +1 more source

Sugar Functionalized Collagen Material for Local Modulation of Innate Immunity

open access: yesAdvanced Science, EarlyView.
Modulation of the innate immune response at the implant site can significantly influence adaptive immunity. A mannose‐functionalized collagen patch, termed the Local Immunotuning Patch (LIP), has been designed to engage mannose receptors on antigen‐presenting cells while exhibiting antibacterial properties. LIP orchestrates complex immune pathways that
Francesca Taraballi   +10 more
wiley   +1 more source

RNA N6-Methyladenine Modification, Cellular Reprogramming, and Cancer Stemness. [PDF]

open access: yesFront Cell Dev Biol, 2022
Chen H   +5 more
europepmc   +1 more source

Enhanced Activities of OCT4 and SOX2 Promote Epigenetic Reprogramming by Shortening G1 Phase

open access: yesAdvanced Science, EarlyView.
Fusing the VP16 domain to OCT4 and SOX2 (OvSvK) enhances iPSC generation by activating downstream targets, including those regulating the cell cycle. This accelerates reprogramming by shortening the G1 phase and reducing H3K27me3 levels. Modulating Ccnd1, Cdkn2a, and Ccne1 improves efficiency, linking cell cycle to epigenetic remodeling.
Lin Guo   +17 more
wiley   +1 more source

Production of an induced pluripotent stem cell line CSSi018-A (14192) from a patient with hypomyelinating leukodystrophy 7 (HLD7) carrying biallelic variants of POLR3A (c.1802 T > A; c.4072G > A)

open access: yesStem Cell Research
Hypomyelinating leukodystrophies (HLD) are a group of heterogeneous genetic disorders characterized by a deficit in myelin deposition during brain development.
Alessia Casamassa   +15 more
doaj  

Cellular reprogramming and epigenetic rejuvenation. [PDF]

open access: yesClin Epigenetics, 2021
Simpson DJ, Olova NN, Chandra T.
europepmc   +1 more source

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