Results 171 to 180 of about 23,277,623 (249)
British Journal of Clinical Pharmacology, EarlyView.Aims This study looks at the status of the same drugs conditionally approved by the Food and Drug Administration and Health Canada for the same oncology indication. Methods Lists of oncology drugs with a conditional approval from the Food and Drug Administration and Health Canada were generated and drug pairs with the same indication were matched ...
Joel Lexchin
wiley +1 more source
Efficient Estimation Methods for the QR Distribution with Type-II Censored Data: An Empirical Validation on Lung Cancer Prognosis. [PDF]
Entropy (Basel)Ramzan Q, Amin M, Alghamdi S, Alharbi R.
europepmc +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Predetermined treatment duration limits (PTDLs) are often used by Taiwan's National Health Insurance Administration to contain healthcare costs, but they may compromise patient outcomes. Therefore, we studied Taiwan's 2017 extension of the bevacizumab PTDL from 24 to 36 weeks in metastatic colorectal cancer (mCRC) to evaluate whether prolonged ...
Wei‐Ming Huang +6 more
wiley +1 more source
A Support vector machine-based mixture cure model for mixed case interval censored data. [PDF]
Stat ComputPal S, Aselisewine W.
europepmc +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims The aim of the study is to describe the use of immune checkpoint inhibitors (ICIs) for the treatment of cancer in Scotland. Methods The retrospective observational cohort study included patients aged 18 years or older who commenced treatment with an ICI in Scotland between 1 January 2018 and 31 December 2024.
Tanja Mueller +9 more
wiley +1 more source
Commensurate prior models with random effects for interval-censored data to accommodate historical controls. [PDF]
Commun Stat Simul ComputFang X +8 more
europepmc +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aim To assess the impact of parameter settings when using the individualized dispensing patterns (IDP) method to estimate exposure duration from dispensing data. Methods We conducted a cohort study using a 2% representative sample of the French healthcare insurance database from 2013 to 2022.
Laëtitia Gosselin +8 more
wiley +1 more source
Censored-Data-Aware Screening of Hazardous Metal(loid)s in Wild Mushrooms from Urban and Peri-Urban Green Spaces: Multielement Fingerprints and Adult Exposure Assessment. [PDF]
J XenobiotPeña-Fernández A +7 more
europepmc +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims The glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) semaglutide and liraglutide are approved for chronic weight management. Both drugs also have favourable effects on the risk of developing diabetes and cardiovascular disease (CVD) compared with placebo, but their comparative effectiveness for these outcomes is unclear.
Ethan J. Cannon +7 more
wiley +1 more source
Checking the Cox Proportional Hazards Model with Interval-Censored Data. [PDF]
J Am Stat AssocXu Y, Zeng D, Lin DY.
europepmc +1 more source