Results 131 to 140 of about 79,005 (311)

Clinical Outcomes and Patient Experiences With Celiprolol Therapy in Vascular Ehlers–Danlos Syndrome: The First Non‐European Cohort

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Vascular Ehlers–Danlos syndrome (vEDS) is a hereditary connective tissue disorder caused by heterozygous pathogenic variants in COL3A1. European studies have shown that celiprolol may reduce the risk of life‐threatening vascular events, but outcomes in non‐European populations and the therapy's psychological impact remain unclear. We conducted
Megumi Furuhata‐Yoshimura, Tomomi Yamaguchi, Tomoki Kosho   +2 more
wiley   +1 more source

Analysis of Receiver Operating Characteristic Curves for Cure Survival Data and Mismeasured Biomarkers

Mathematics
Cure models and receiver operating characteristic (ROC) curve estimation are two important issues in survival analysis and have received attention for many years.
Li-Pang Chen
doaj   +1 more source

Australian Activists as Storytellers in Digital Spaces: Acquiring Skills, Producing Content and Getting the Message Out

Australian Journal of Social Issues, EarlyView.
ABSTRACT As modes of activism rapidly evolve, activists—both seasoned and emerging—must increasingly navigate a hybrid terrain of both digital and non‐digital engagement. This paper draws on the personal narratives of 16 nascent activists based in Australia to explore how they develop competencies related to digital storytelling, which is critical to ...
Garth Stahl, Miri Yemini, Claire Maxwell, Yating Hu, Benjamin Adams, Sarah Bergen   +5 more
wiley   +1 more source

Long‐term prognosis is associated with residual disease after neoadjuvant systemic therapy but not with initial nodal status

BJS (British Journal of Surgery), EarlyView., 2020
This long‐term follow‐up study determined survival rates in a Swedish national cohort of 417 patients with breast cancer who all had neoadjuvant systemic therapy (NAST). Sentinel lymph node biopsy (SLNB) was performed before NAST in clinically node‐negative and after NAST in clinically node‐positive patients.
L. Zetterlund, F. Celebioglu, T. Hatschek, J. Frisell, J. de Boniface   +4 more
wiley   +1 more source

Failure censoring, progressive type II censoring and distribution family with bathtub shape hazard rate

, 2010
碩士在第一章，我們討論失效篩選取樣及逐次型二篩選取樣的關係，並在失效篩選取樣下分別討論，指數分佈及柏拉圖分佈最佳分組的問題。並且討論了在逐次型二篩選取樣的最佳設計。最後以模擬的方式來討論失效篩選取樣如何決定最佳組內個數。 在第二章，在特殊形式的累積機率分佈下，討論了故障率為浴缸型的分佈族。本文提出了三個具體不同的分佈族。In chapter one, we discuss the relation between failure censoring scheme and progressively ...
王世豪; Wang, Shi-hao
core  

Is it wise to censor the censorable?

Developing World Bioethics, 2020
openaire   +3 more sources

Inflammatory Signatures Beyond Th1/Th2 Endotypes Provide Insights Into Postoperative Recurrence in Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) represents a spectrum of inflammatory endotypes, driven by distinct T helper (Th) immune responses. The high rate of recurrent disease despite appropriate medical and surgical interventions highlights the need for improved characterization beyond the traditional type 2 and non‐type 2 phenotypes to better
Liyona Kampel, Narin N. Carmel, Shaun Edalati, Hen Chaushu, Forsan Jahshan, Yaniv Hadi, Timur Pestrikov, Leonor Leider Trejo, Nidal Muhanna, Avraham Abergel   +9 more
wiley   +1 more source

Daily‐Life, Sensor‐Derived Tremor Measures Are Sensitive to Progression in Early Parkinson's Disease

Annals of Neurology, EarlyView.
Objective Sensitive outcome measures are critical for evaluating the efficacy of novel treatments for Parkinson's disease (PD). In this study, we assess the sensitivity to change of sensor‐derived daily‐life tremor measures over 2 years in unmedicated and medicated persons with early PD.
Nienke A. Timmermans, Ioan Gabriel Bucur, Diogo C. Soriano, Erik Post, Hayriye Cagnan, Sooyoon Shin, Max A. Little, Yordan P. Raykov, Bastiaan R. Bloem, Rick C. Helmich, Luc J.W. Evers   +10 more
wiley   +1 more source

MIDDLE CENSORING IN THE PRESENCE OF COVARIATES [PDF]

, 2014
Middle censoring refers to data that becomes unobservable if it falls within a random interval (L,R). For some individuals the exact values are available while for others the corresponding intervals of censorship are observed.
Leong, Elvynna
core  

Cerebrospinal Fluid Amyloid‐β Biomarkers Predict Future Hemorrhage in Patients with Cerebral Amyloid Angiopathy

Annals of Neurology, EarlyView.
Objective Accurately predicting future hemorrhagic events in patients with cerebral amyloid angiopathy (CAA) remains a major clinical challenge. It is unknown whether cerebrospinal fluid (CSF) biomarkers of amyloid‐beta (Aβ) pathology are associated with increased hemorrhage risk in this population.
Philipp Arndt, Malte Pfister, Valentina Perosa, Hendrik Mattern, Melis Tas, Lara Holzheimer, Johanna Engel, Marc Dörner, Marwa Al‐Dubai, Cornelia Garz, Eya Khadhraoui, Sebastian J. Müller, Patrick Müller, Sven G. Meuth, Katja Neumann, Stefanie Schreiber   +15 more
wiley   +1 more source