Results 31 to 40 of about 71,213 (265)
Fiducial Inference on the Right Censored Birnbaum–Saunders Data via Gibbs Sampler
Stats, 2021 In this article, we implement a flexible Gibbs sampler to make inferences for two-parameter Birnbaum–Saunders (BS) distribution in the presence of right-censored data.
Kalanka P. Jayalath
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak +9 more
wiley +1 more source
A Note on Weibull Parameter Estimation with Interval Censoring Using the EM Algorithm
Mathematics, 2023 In many engineering applications, it is often the case that the observations are only available in interval form. In this note, by using the expectation-maximization (EM) algorithm, the parameter estimation of the Weibull distribution with interval ...
Chanseok Park
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Journal of Statistical Software, 2012 In many medical studies, patients can experience several events. The times between consecutive events (gap times) are often of interest and lead to problems that have received much attention recently.
Ana Moreira, Luis Meira-Machado
doaj
The Impact of Interval Choice in Grouped Frequency Tables on Statistical Modelling [PDF]
Statistika: Statistics and Economy JournalThis paper examines the adequacy of grouped (interval) frequency tables for statistical modelling. Inspired by the chosen real-world data structure, the research question is: Can accurate modelling be achieved with the given grouping schemes without a ...
Adam Čabla
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi +9 more
wiley +1 more source
SAS Macros for Calculation of Population Attributable Fraction in a Cohort Study Design
Journal of Statistical Software, 2011 The population attributable fraction (PAF) is a useful measure for quantifying the impact of exposure to certain risk factors on a particular outcome at the population level.
Maarit A. Laaksonen +4 more
doaj