Results 171 to 180 of about 6,470 (259)

Challenges and Opportunities in Cancer Screening in Incarcerated Populations. [PDF]

J Am Coll Radiol
Kaiksow FA, Striker R, LoConte NK.
europepmc   +1 more source

Sproglig censur - censur sprogligt

, 2015
openaire   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Graduate Medical Education Data in the United States: Availability and Accessibility Across National Organizations. [PDF]

J Grad Med Educ
Thelen AE, Gates RS, Khamees D, Haas MRC, Pradarelli AA, Burkhardt J, Krumm AE, Weinstein D, George BC.   +8 more
europepmc   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

The Essential Role of Medical Monitors in Clinical Trials. [PDF]

Cureus
Klein GL, Barabash E, Morgan RE, Brown G, Tulchinskiy M, Byrth F, Jones Amaowei E, Vukojevic P, Vaezzadeh S, Dawson KL, Cohn G, Haworth S, Blackwood-Chirchir A, Wolff J, Overton A.   +14 more
europepmc   +1 more source

L’audiovisuel arabe entre censure et auto-censure

, 2022
Saiegh, Marc, Saiegh, Marc > Auteur
openaire   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

General medicine wards and the mental health crisis: invisible and unsafe. [PDF]

Intern Med J
Towns C, Hodgetts K, Shirtcliffe P, Cameron C, Sekicki V, McCloy C, Giedt C, Lourens N, Putt T.   +8 more
europepmc   +1 more source