Results 91 to 100 of about 21,026 (285)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
From the Banned Telefilm to the Feature Film: the Two Versions of Alan Clarke’s Scum (1977-1979)
Revue LISA, 2013 Alan Clarke’s Scum, originally made for the BBC’s Play for Today series in 1977, has become a cause célèbre in the history of film censorship. Although the film had already been scheduled, it was eventually banned and only broadcast in 1991, a year after
Nicole Cloarec
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
L'Âge d'or, 2009 Francisco Ortiz Muñoz a prononcé à Madrid en 1946 une conférence qu’il a ensuite publiée sous le titre Criterios y normas morales de censura cinematográfica. Conferencia pronunciada en el Salón de Actos del Consejo Superior de Investigaciones Científicas
Julia Tuñón
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
, 2010 Le séminaire littérature et censure étudie les diverses formes de censure qui s’exercent sur la littérature, selon des critères juridiques, financiers, éthiques, idéologiques ou esthétiques, et leurs effets sur la genèse des œuvres, en particulier par l ...
core
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Censure: Moral and Sociological [PDF]
, 2017 The concept of censure, as developed in different ways, in the work of Sumner and von Hirsch, has enormous potential—though each of the accounts has its own limitations—In this chapter, I discuss both theories and show some way in which there is a common ground between them, and to offer some suggestions as to ways that this common ground might be ...
openaire +1 more source