Results 51 to 60 of about 6,573 (256)
Histoire, cinéma et idéologie : réflexions sur le Cimarron de Wesley Ruggles (1930)
Wesley Ruggles’s film adaptation of Edna Ferber’s eponymous novel deals with the question of slavery. Glorifying the right to set up, it eternalizes the famous uncivilized racing of 50 000 would-be farmers in quest of a piece of land in Oklahoma.
Elyette Benjamin-Labarthe
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Une bande dessinée adulte ? Usages et mésusages de la légitimation
Cet article revisite la question de la légitimation telle que Luc Boltanski la mobilise pour analyser la constitution du champ de la bande dessinée dans le premier numéro des Actes de la recherche en sciences sociales.
Sylvain Lesage
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Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Pascale Budillon Puma écrit une belle page d’humour sur un certain type de vocabulaire incontournable de la vie courante et pourtant délicat à enseigner et à expliquer aux étudiants.
Pascale Budillon Puma
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Le vaudeville sous la Deuxième République : une arène ouverte aux passions politiques ?
Lorsqu’on supprima la censure en 1848, on assista à un foisonnement de pièces à sujet politique, notamment au théâtre du Vaudeville. Ces satires politiques connurent d’importants succès, soulignant le rôle du vaudeville comme miroir parodique de la ...
Janice Best
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Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Mémoire : plaidoyer et réquisitoire d’un auteur moraliste
Dans Mémoire, Montherlant se défend des accusations portées contre lui pendant l’Occupation. Ce texte écrit à la Libération ne sera publié qu’en 1976, après la mort de l’auteur.
Adrien Vezzoso
doaj +1 more source

