Results 61 to 70 of about 6,693 (256)
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
The proportionality between crime and punishment is made, and the way it is made makes for a certain kind of criminal law. By analyzing how punitive measures are justified in Swedish criminal law and crime policy through appeals to proportionality, the ...
Sigrid Nikka
doaj +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
À propos de la Manía de citas y de epígrafes (1832) de Mariano José de Larra
Dans cet article est effectuée une lecture philologique d’un court texte satirique de l’écrivain romantique espagnol Mariano José de Larra, la Manía de citas y de epígrafes (1832).
Antoni Ferrer
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
L’adaptation des bandes dessinées américaines et italiennes en France dans les années 1930 et 1940
The creation of the Journal de Mickey in 1934 gives the signal to the introduction of foreign comics in France. First American and then Italian, these works will invite children publishers to question the inclusion of these images in a new editorial ...
Thierry Crépin
doaj
Tutela de los menores de edad y libertad de prensa en Francia. El caso de las bandes dessinées [PDF]
The French comic-books have a long tradition, but as they are mainly addressed to youth people, they are subjected to a State control. This control is in the hands of a Commission (Commission de surveillance et de contrôle des publications destinées à l ...
Ignacio Fernández Sarasola
doaj
This article proposes a first approach to uses and meanings of scandal in the Golden Age, understood here as a specific type of heterodoxy, a form of dissent, one of the categories of propositiones damnabiles and hence an instrument of censorship that ...
María José Vega
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Contestation, no censure: Motions in post-communist Romania (1989-2008)
Confidence motions introduced in the Romanian Parliament in 1989-2008 represented important tools of legislative control over the executive. Simple and censure motions employed by the opposition against the government tackled the most important issues ...
Lavinia Stan, Diane Vancea
doaj

