Results 81 to 90 of about 16,197 (298)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
From the Banned Telefilm to the Feature Film: the Two Versions of Alan Clarke’s Scum (1977-1979)
Alan Clarke’s Scum, originally made for the BBC’s Play for Today series in 1977, has become a cause célèbre in the history of film censorship. Although the film had already been scheduled, it was eventually banned and only broadcast in 1991, a year after
Nicole Cloarec
doaj +1 more source
De la censure théâtrale à la censure cinématographique
La censure reprenant son ancienne besigne, par Cham (1852), Bibliothèque de Bordeaux. 12 décembre 2013 par Patrick Désile (CNRS) Bibliographie - Odile Krakovitch, Censure des répertoires des grands théâtres parisiens (1835-1906 ...
Nicolas Schmidt
core
International audienceLa censure n’est plus ce qu’elle était. La liberté d’expression ne fait plus l’unanimité, l’Église ou l’État ne sont plus seuls à censurer, les opérations de filtrage des opinions se sont privatisées, les média visuels et l’internet
Brun, Catherine, Roussin, Philippe
core
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Francisco Ortiz Muñoz a prononcé à Madrid en 1946 une conférence qu’il a ensuite publiée sous le titre Criterios y normas morales de censura cinematográfica. Conferencia pronunciada en el Salón de Actos del Consejo Superior de Investigaciones Científicas
Julia Tuñón
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Le groupe interdisciplinaire de doctorants moniteurs de l’Université d’Aix-Marseille organise, le 18, 19 et 20 novembre 2008 à la Maison Méditerranéenne des sciences de l’homme d’Aix-en-Provence, un colloque autour du thème de la censure à l’époque contemporaine.
openaire +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source

