Results 121 to 130 of about 20,835 (289)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Dialogue avec les censeurs : À propos de : Robert Darnton, De la censure. Essai d’histoire comparée, Gallimard

open access: yes, 2016
Recension / Compte-rendu.Compte-rendu de: Robert Darnton, De la censure. Essai d’histoire comparée, trad. Jean-François Sené, Paris, Gallimard, coll. « NRF essais », 2014.Résumé de l'éditeur: la censure, selon Robert Darnton, n’entrave pas toujours la ...
Amadieu, Jean-Baptiste
core   +3 more sources

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Préface des coordinatrices

open access: yesConnexe, 2022
Valentina Calzolari, Claire Mouradian
doaj   +1 more source

Rencontres Droit et cinéma : Censure et cinéma

open access: yes, 2011
Les Vemes rencontres Droit et cinéma se dérouleront les 29 et 30 juin 2012 à l'Université de la Rochelle. Le thème choisi est celui de la censure. Voici le texte de l'appel à communications: nul doute que les sujets traités seront passionants et que je ...
Jean-Baptiste THIERRY
core  

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Post-censures ?

open access: yesCalenda, 2019
La foi dans les vertus et les bénéfices sociaux de la liberté d’expression et du free speech a été largement remise en cause et une critique du paradigme dominant de la manière de penser la liberté d’expression et la censure a vu le jour, dont on a pu regrouper les diverses manifestations sous le label de « New Censorship Theory ».
openaire   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

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