Results 111 to 120 of about 21,026 (285)
La lettre comme moyen de dénonciation : étude de « Pour la liberté de pensée »de Voltaire
Revista de Lenguas Modernas, 2010 Dans l’une de ces nombreuses lettres intitulée Pour la liberté de pensée nous étudierons les raisons pour lesquelles Voltaire considère qu’il ne faut pas interdire les livres. Pour ce faire, nous analyserons les outils linguistiques utilisés par l’auteur
Beatriz Rodríguez Oconitrillo
doaj
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Censure royale et censure épiscopale : le conflit de 1702
, 1976 John Woodbridge : Royal and episcopal censorship. The conflict of 1702. On 25th November 1702, the Chancellor Pontchartrain and the Archbishop of Paris, Noailles, settled a dispute, arising from Bossuet's attempts to censor R.
Woodbridge, John, John Woodbridge
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Combattre la censure, est-ce vouloir supprimer toute censure ? S’il en était ainsi, les affaires seraient simples, les questions inutiles. Que l’on veuille bien sonder sinon les coeurs et les têtes, du moins sa propre conduite et les maximes qui la ...
Levreaud, Philippe
core
The Constitutionality of Censure [PDF]
, 1998 It has become commonplace for commentators to suggest that, in the aftermath of the Senate\u27s acquittal of President William Jefferson Clinton, there have been only losers and no real winners.
Gerhardt, Michael J.
core +2 more sources
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
, 1974 Galliani R. Mably et la censure. In: Annales historiques de la Révolution française, n°217, 1974. pp.
Galliani, R.
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source