Results 151 to 160 of about 21,026 (285)

'What are you in for?' The neglected role of the offence in prison sociology. [PDF]

Incarceration
Jarman B, Ievins A, Crewe B.
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Characterization of cases and analysis of First-instance Judgments in Ethical Proceedings at the Regional Council of Veterinary Medicine of the State of São Paulo. [PDF]

Braz J Vet Med
Ruiz RT, Bosch RV, Stringari S, Ruiz JLM, Maiorka PC.   +4 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Opening the black box of the Spanish legislative Process: The Legislative Amendments Dataset (1996-2023). [PDF]

Data Brief
Palau AM, Casas A, Muñoz L, Rodilla A.
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

La censure militaire et policière, 1914-1918

, 2014
RAJSFUS Maurice La censure militaire et policière, 1914-1918 Paris : Le Cherche midi, 2014, 327 p. Collection Documents ISBN 978-2-7491-3575-5 FR 1681 Résumé éditeur : Dès les premiers jours de la Grande Guerre, la censure est instaurée et cette mesure ...
Nordoc'Archéo
core  

Punishing to Send a Message ^†. [PDF]

Oxf J Leg Stud
Ryu A, Sewell T.
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Censures

, 2013
Dossier de revue comportant les articles suivants : 1. Pascal Durand (Université de Liège), « La censure au pluriel »; 2. Jean-Pierre Cavaillé (École des Hautes Études en Sciences Sociales), « Censure et acceptabilité des énoncés religieux à l’époque médiévale et sous l’ancien régime.
openaire   +1 more source