Results 131 to 140 of about 6,577 (256)

Confronting federal censorship of social vulnerability index. [PDF]

Lancet Reg Health Am
Huang SJ, McCoy RG.
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Folsom Transplant Blues: What is wrong with offering the incarcerated shorter sentences for donating organs and bone marrow? [PDF]

J Law Med Ethics
Albertsen A, Thaysen JD.
europepmc   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Prevalence and factors associated with research misconduct among faculty in selected public universities in Eastern Uganda: a cross-sectional study. [PDF]

Discov Educ
Ayikobua ET, Munabi IG, Nabukenya S, Opito R, Mwaka ES.   +4 more
europepmc   +1 more source

The untitled editorial. [PDF]

Can Liver J, 2023
Yoshida EM, Chandok N.
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Where is the Power in a Power Analysis? [PDF]

Int J Exerc Sci
Dames KD, Climenhaga Z, Rosenberg J.
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Explainable and reproducible AI: culturally responsive AI for health equity in minoritized groups. [PDF]

Front Digit Health
King-Okoye M, Fuller H, Tan K, Marlow N, Fleuriot J, Tzatzakis C, Kanodia S, Odoh K, Dubbala K, Alvarez JA.   +9 more
europepmc   +1 more source