Results 201 to 210 of about 6,693 (256)

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

Addressing harmful gender norms in sexual health services. [PDF]

open access: yesBull World Health Organ
Morgan R   +4 more
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source
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The Censure

2005
Abstract This chapter is occupied with an examination of the first Dominican censure against Durandus in 1314, which represents the climax of the conflict. The articles concerning Durandus’s Trinitarian theology show how Durandus’s thesis of a real distinction between the divine essence and relations was perceived as a natural ...
exaly   +2 more sources

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