Conversión de prueba cutánea de derivado proteico purificado durante el tratamiento con anti-TNF-α
Revista Argentina de Reumatología, 2021 Introducción: los anti-TNF-α se asocian con mayor riesgo de desarrollar tuberculosis (TB). La prueba del derivado proteico purificado (purified protein derivative, PPD) se emplea para diagnosticar infección de tuberculosis latente (ITL).
Brian Marcelo Abdala +15 more
doaj +1 more source
Infectious Disease Reports, 2022 During the first year of the COVID-19 pandemic, unauthorized drugs were widely used. Ivermectin and hydroxychloroquine are drugs that inhibit viral replication in vitro and that have been used in several medical centers.
Jose Lenin Beltran Gonzalez +12 more
doaj +1 more source
Valvoplastia mitral percutânea por balão: evolução a longo prazo e análise dos fatores de risco para óbito e eventos maiores [PDF]
Arquivos Brasileiros de Cardiologia, 2005 OBJETIVO: Identificar os fatores, que predizem óbito e eventos combinados de óbito, nova valvoplastia mitral por balão ou cirurgia valvar mitral a longo prazo, nos pacientes submetidos à valvoplastia mitral percutânea por balão.
Ivana Picone Borges +8 more
doaj +3 more sources
Co-Expression of Wild-Type P2X7R with Gln460Arg Variant Alters Receptor Function [PDF]
, 2016 The P2X7 receptor is a member of the P2X family of ligand-gated ion channels. A single-nucleotide polymorphism leading to a glutamine (Gln) by arginine (Arg) substitution at codon 460 of the purinergic P2X7 receptor (P2X7R) has been associated with mood ...
Acuña, Matias +15 more
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Scientific Reports, 2021 This work aimed to investigate the partial K-replacement by Na supply to alleviate drought-induced stress in Eucalyptus species. Plant growth, leaf gas exchange parameters, water relations, oxidative stress (H2O2 and MDA content), chlorophyll ...
Nikolas Souza Mateus +9 more
doaj +1 more source
Structural Insights into the HWE Histidine Kinase Family: The Brucella Blue Light-Activated Histidine Kinase Domain [PDF]
, 2016 In response to light, as part of a two-component system, the Brucella blue light-activated histidine kinase (LOV-HK) increases its autophosphorylation, modulating the virulence of this microorganism.
Arrar, Mehrnoosh +9 more
core +1 more source
A genetic toolkit for the analysis of metabolic changes in Drosophila provides new insights into metabolic responses to stress and malignant transformation [PDF]
, 2019 Regulation of the energetic metabolism occurs fundamentally at the cellular level, so analytical strategies must aim to attain single cell resolution to fully embrace its inherent complexity.
Behrensen, C. +3 more
core +1 more source
A Novel Genetic Screen Identifies Modifiers of Age-Dependent Amyloid β Toxicity in the Drosophila Brain [PDF]
, 2017 The accumulation of amyloid β peptide (Aβ) in the brain of Alzheimer's disease (AD) patients begins many years before clinical onset. Such process has been proposed to be pathogenic through the toxicity of Aβ soluble oligomers leading to synaptic ...
Belfiori Carrasco, Lautaro Francisco +5 more
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The Endoplasmic Reticulum Glucosyltransferase Recognizes Nearly Native Glycoprotein Folding Intermediates [PDF]
, 2004 The UDP-Glc:glycoprotein glucosyltransferase (GT), a key player in the endoplasmic reticulum (ER) quality control of glycoprotein folding, only glucosylates glycoproteins displaying non-native conformations.
Caramelo, Julio Javier +3 more
core +1 more source